Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

34 questions · 57 findings · 2 reviews · Incontinence

No studies found 4 · 7%GRADE not reported 4 · 7%Very low 30 · 52.6%Low 14 · 24.6%Moderate 5 · 8.8%High 0 · 0%

Alarm vs miscellaneous treatments

Proportion of children dry at · children with nocturnal enuresis

It is very uncertain whether alarm changes proportion of children dry at compared with miscellaneous treatments (very low certainty).

2 findings from 1 review

Alarm vs placebo drug

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

Alarm may leads to higher proportion of children achieving 14 consecutive dry nights by the… compared with placebo drug (low certainty).

1 finding from 1 review

Alarm plus other intervention vs other interventions

Proportion of children achieving 14 consecutive dry nights by the end of treatment · children with nocturnal enuresis

It is very uncertain whether alarm plus other intervention changes proportion of children achieving 14 consecutive dry nights by the… compared with other intervention (very low certainty).

3 findings from 1 review

Alarm plus other intervention vs other interventions

Proportion of children dry at · children with nocturnal enuresis

Alarm plus other intervention showed no clear difference in proportion of children dry at compared with other intervention (low certainty).

2 findings from 1 review

Tricyclic antidepressants vs behavioural interventions

Number not achieving 14 consecutive dry nights at the end of treatment ‐ amitriptyline vs placebo · children with nocturnal enuresis

It is very uncertain whether tricyclics changes number not achieving 14 consecutive dry nights at the end of… compared with behavioural interventions (very low certainty).

2 findings from 1 review