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What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

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No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Chlorhexidine vs povidone‐iodine

Adverse events (maternal) ‐ skin irritation or allergic skin reaction · women undergoing caesarean section

It is very uncertain whether chlorhexidine gluconate changes adverse events (maternal) ‐ skin irritation or allergic skin reaction compared with povidone iodine (very low certainty).

1 finding from 1 review

Dopamine‐milrinone vs dopamine‐dobutamine

All‐cause short‐term mortality: at intensive care unit · adults with cardiogenic shock

It is very uncertain whether dopamine‐milrinone changes all‐cause short‐term mortality: at intensive care unit compared with dopamine‐dobutamine (very low certainty).

1 finding from 1 review

Epinephrine vs norepinephrine‐dobutamine

All‐cause short‐term mortality: 28 days · adults with cardiogenic shock

It is very uncertain whether epinephrine changes all‐cause short‐term mortality: 28 days compared with norepinephrine‐dobutamine (very low certainty).

1 finding from 1 review

More intensive vs less intensive insulin therapy

Transplant or graft survival · pre‐existing and new‐onset diabetes in kidney transplant recipients

It is very uncertain whether more intensive changes transplant or graft survival compared with less intensive insulin therapy (very low certainty).

1 finding from 1 review