Vomiting · adults and children with drug‐resistant focal epilepsy
Any dose of lacosamide probably leads to higher vomiting compared with placebo (moderate certainty).
1 finding from 1 review
Serious adverse events · adults and children with drug‐resistant focal epilepsy
Any dose of lacosamide probably leads to higher serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
FEV1 % predicted: absolute change from baseline · children and young adults with CF
1 finding from 1 review
FEV1 % predicted: absolute change from baseline · children and young adults with CF
1 finding from 1 review
FVC (% predicted) Change from baseline · children and young adults with CF
1 finding from 1 review
Height velocity (cm/year) · children and young adults with CF
1 finding from 1 review
Change in weight (kg) · children and young adults with CF
1 finding from 1 review
QoL · children and young adults with CF
1 finding from 1 review
FVC (% predicted) Change from baseline · children and young adults with CF
1 finding from 1 review
Fasting blood glucose (mg/dL) · children and young adults with CF
1 finding from 1 review
Number of pulmonary exacerbations or hospitalisations · children and young adults with CF
High‐dose rhGH showed no clear difference in number of pulmonary exacerbations or hospitalisations compared with placebo (low certainty).
1 finding from 1 review
Height velocity (cm/year) · children and young adults with CF
1 finding from 1 review
Change in weight (kg) · children and young adults with CF
1 finding from 1 review
QoL · children and young adults with CF
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Fasting blood glucose (mg/dL) · children and young adults with CF
1 finding from 1 review
Number of pulmonary exacerbations or hospitalisations · children and young adults with CF
Standard rhGH showed no clear difference in number of pulmonary exacerbations or hospitalisations compared with placebo (low certainty).
1 finding from 1 review
Urinary protein or albumin excretion ‐ total albumin excretion at 6 months · People with proteinuria or microalbuminuria due to sickle cell disease
1 finding from 1 review
Creatinine level · People with proteinuria or microalbuminuria due to sickle cell disease
1 finding from 1 review
Electrolyte levels · People with proteinuria or microalbuminuria due to sickle cell disease
1 finding from 1 review
Blood pressure · People with proteinuria or microalbuminuria due to sickle cell disease
1 finding from 1 review