Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,751 questions · 12,775 findings · 807 reviews · Headline outcomes only

No studies found 3,413 · 26.7%GRADE not reported 709 · 5.5%Very low 3,483 · 27.3%Low 3,165 · 24.8%Moderate 1,628 · 12.7%High 377 · 3%

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SSRI antidepressants vs tricyclic antidepressants (TCAs)

Drop‐out Objective · Adults with mental disorders in low‐ and middle‐income countries

It is very uncertain whether SSRI antidepressants changes drop‐outs (12 weeks) compared with TCA (very low certainty).

1 finding from 1 review

Metformin vs placebo

Fasting blood glucose (mg/dL) · Adults with mental disorders in low‐ and middle‐income countries
2 findings from 1 review

Intervention not reported

Incidence of delirium during hospital admission validated diagnostic instruments1 3693 participants (14 studies)

The intervention probably leads to lower incidence of delirium during hospital admission validated diagnostic… (moderate certainty).

1 finding from 1 review