Findings

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Package of oral health education/promotion including oral hygiene advice for pregnant women, mothers, infants and young children, plus dietary and feeding practice advice for infants and young children vs usual care

Child microbiological presence (any mutans streptococci colonisation) · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

Package of oral health education/promotion including oral hygiene… showed no clear difference in child microbiological presence (mutans streptococci colonisation) compared with standard care; GRADE not reported.

1 finding from 1 review

Chin cup (600 g force) vs Chin cup (300 g force)

ANB · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Chin cup (600 g force) showed no clear difference in ANB compared with chin cup (300 g force); GRADE not reported.

1 finding from 1 review

Pentoxifylline vs Placebo or no active treatment

Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

It is very uncertain whether pentoxifylline changes burning sensation (VAS 0-100) compared with placebo or no active treatment (very low certainty).

1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

Any adverse effect related to aPDT · Adults (> 18 years) with recurrent periodontitis, receiving supportive (maintenance) periodontal care
1 finding from 1 review

Package of oral health education/promotion including oral hygiene advice for pregnant women, mothers, infants and young children, plus dietary and feeding practice advice for infants and young children vs usual care

SiC30 index score · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

Package of oral health education/promotion including oral hygiene… led to lower siC30 index score compared with standard care; GRADE not reported.

1 finding from 1 review

Facemask vs no intervention

Perceived need for surgery in adulthood · Children and adolescents (aged 16 years or younger) with prominent lower front teeth (Class III malocclusion)

Facemask may leads to higher perceived need for surgery in adulthood compared with untreated control (no treatment) (low certainty).

1 finding from 1 review

Single preoperative dose of systemic antibiotics (clindamycin 600 mg), total chemo-mechanical debridement and root filling vs Matched placebo, total chemo-mechanical debridement and root filling

Pain at 7 days · Adults with symptomatic apical periodontitis (no signs of spreading infection or systemic involvement)
1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Mother caries (dmfs increment) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution… showed no clear difference in mother caries (dmfs increment) compared with placebo; GRADE not reported.

1 finding from 1 review

Postoperative systemic antibiotics (phenoxymethylpenicillin/penicillin VK, 7-day course), partial or total chemo-mechanical debridement and analgesics vs Matched placebo, partial or total chemo-mechanical debridement and analgesics

Endodontic flare-up · Adults with a symptomatic necrotic tooth or localised acute apical abscess (no signs of spreading infection or systemic involvement)

Postoperative systemic antibiotics… showed no clear difference in endodontic flare-up compared with matched placebo, partial or total chemo-mechanical debridement and…; GRADE not reported.

1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after submucosal instrumentation (SI) vs Submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT

Change in bleeding on probing (BOP) · Adults (> 18 years) with peri-implant mucositis, receiving active treatment

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… led to higher change in bleeding on probing (BOP) compared with submucosal instrumentation (SI) alone, or SI plus placebo/sham aPDT; GRADE not reported.

1 finding from 1 review

Oxitard (antioxidant) vs Topical aloe vera gel

Difficulty in swallowing (participant-reported proxy) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)

Oxitard (antioxidant) led to lower difficulty in swallowing (participant-reported proxy) compared with aloe vera gel; GRADE not reported.

1 finding from 1 review

Occlusal splint vs Behavioural therapy (counselling, CBT, relaxation, self-care management)

Participant satisfaction or quality of life · People with temporomandibular disorders (TMD)

Occlusal splint showed no clear difference in participant satisfaction or quality of life compared with behavioural therapy (counselling, CBT, relaxation, self-care…; GRADE not reported.

1 finding from 1 review