Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

573 questions · 608 findings · 115 reviews

No studies found 136 · 22.4%GRADE not reported 54 · 8.9%Very low 166 · 27.3%Low 152 · 25%Moderate 75 · 12.3%High 25 · 4.1%

Thrombopoietin mimetics vs placebo or usual care

Number of participants with severe or life‐threatening bleeding · people with haematological disorders undergoing intensive chemotherapy or stem cell transplantation

It is very uncertain whether thrombopoietin mimetics changes number of participants with severe or life‐threatening bleeding compared with placebo or standard care (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants with at least 1 bleeding episode · people with haematological disorders undergoing intensive chemotherapy or stem cell transplantation

It is very uncertain whether the intervention changes number of participants with at least 1 bleeding episode (very low certainty).

1 finding from 1 review

Intervention not reported

Combined mortality of all studies · Adult patients in intensive care

The intervention leads to higher combined mortality of all studies (high certainty).

1 finding from 1 review

Community pharmacy personnel interventions vs standard care or less intensive support

Smoking cessation · people who smoke who were motivated to change their smoking behavior

Community pharmacy personnel interventions may leads to higher smoking cessation compared with standard care or less intensive support (low certainty).

1 finding from 1 review