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Evidence found and GRADE certainty

4,721 questions · 19,640 findings · 2,039 reviews · Headline outcomes only

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No studies found 3,754 · 19.1%GRADE not reported 1,273 · 6.5%Very low 4,859 · 24.7%Low 5,568 · 28.4%Moderate 3,240 · 16.5%High 946 · 4.8%

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Summary of findings table ‐ Progestogens vs GnRH agonist

Oocyte pick‐up cancellation · assisted reproduction technology cycles

Summary of findings table ‐ Progestagen showed no clear difference in oocyte pick‐up cancellation compared with gnRH agonist (low certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH agonist

Moderate or severe OHSS · assisted reproduction technology cycles

It is very uncertain whether summary of findings table ‐ Progestagen changes moderate or severe OHSS compared with gnRH agonist (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs Progestogen 2

Oocyte pick‐up cancellation · assisted reproduction technology cycles

Summary of findings table ‐ Progestogen 1 showed no clear difference in oocyte pick‐up cancellation ‐ Normo‐responders (MPA 4 mg versus… compared with progestogen 2 (low certainty).

5 findings from 1 review
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Summary of findings table ‐ Progestogens vs Progestogen 2

Oocyte pick‐up cancellation ‐ Normo‐responders (Dydrogesterone 20 mg versus Micronised progesterone 100 mg) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles

Summary of findings table ‐ Progestogen 1 showed no clear difference in oocyte pick‐up cancellation ‐ Normo‐responders (Dydrogesterone 20 mg… compared with progestogen 2 (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs Progestogen 2

Miscarriage · assisted reproduction technology cycles

Summary of findings table ‐ Progestogen 1 showed no clear difference in miscarriage ‐ Miscarriage per randomised woman ‐ Normo‐responders… compared with progestogen 2 (low certainty).

1 finding from 1 review

CHG‐IPA vs CHG‐A

Chemical burns or contact dermatitis, measured using a scoring system or by clinical judgement as described by the trial author during or after the application of antiseptic solutions (dermatitis) · neonates that require central line

CHG‐IPA showed no clear difference in chemical burns or contact dermatitis, measured using a scoring… compared with CHG‐A (moderate certainty).

1 finding from 1 review

CHG‐IPA vs PI

Chemical burns or contact dermatitis, measured using a scoring system or by clinical judgement as described by the trial author during or after the application of antiseptic solutions (dermatitis) · neonates that require central line

It is very uncertain whether CHG‐IPA changes chemical burns or contact dermatitis, measured using a scoring… compared with PI (very low certainty).

1 finding from 1 review

Doxapram vs no treatment, placebo, methylxanthine (including theophylline, aminophylline, or caffeine), or

Failed apnea reduction · treatment of apnea

Doxapram showed no clear difference in 1a. Failed apnea reduction after 2–7 days – doxapram compared to no… compared with no treatment, placebo, methylxanthine (including theophylline,… (low certainty).

3 findings from 1 review