Findings

What do systematic reviews say?

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

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No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Intervention not reported

New diagnosis of dementia (at any time point after randomisation) Not measured

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Duration of delirium (days) (any time during hospital admission)

1 finding from 1 review

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 351 participants
Low

Intervention not reported

Delirium severity (any time during hospital admission) validated diagnostic instruments6 147 participants (5 studies)

1 finding from 1 review

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 6 participants
Very low

Intervention not reported

Length of hospital admission (days)

1 finding from 1 review

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients 2021 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 3351 participants
Low

Intervention not reported

Discharge from hospital to new long‐term care placement 536 participants (1 study)

The intervention showed no clear difference in discharge from hospital to new long‐term care placement 536… (low certainty).

1 finding from 1 review

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients 2021 · Cochrane Headline outcomes only
RR 0.77 [0.55, 1.07]
1 study · 536 participants
Low

CVVHD vs CVVH or CVVHDF

Circuit lifespan · AKI patients receiving CKRT

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pre‐dilution vs post‐dilution (as defined by study investigators)

Death from any cause at day 28 of · AKI patients receiving CKRT

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pre‐dilution vs post‐dilution (as defined by study investigators)

Recovery of kidney function · AKI patients receiving CKRT

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pre‐dilution vs post‐dilution (as defined by study investigators)

Vascular access complications · AKI patients receiving CKRT

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Higher blood flow vs standard blood flow

Circuit lifespana · AKI patients receiving CKRT

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 499 participants
Low

Higher blood flow vs standard blood flow

Death from any cause at day 28 of · AKI patients receiving CKRT

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Higher blood flow vs standard blood flow

Recovery of kidney function · AKI patients receiving CKRT

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Higher blood flow vs standard blood flow

Vascular access complications · AKI patients receiving CKRT

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Long (> 20 cm) vs short (≤ 20 cm) catheter

Circuit lifespana · AKI patients receiving CKRT

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 402 participants
Low

Long (> 20 cm) vs short (≤ 20 cm) catheter

Death from any cause at day 28 of · AKI patients receiving CKRT

It is very uncertain whether long (> 20 cm) changes death from any cause at day 28 of compared with short (≤ 20 cm) catheter (very low certainty).

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
RR 1.38 [0.61, 3.11]
1 study · 94 participants
Very low

Long (> 20 cm) vs short (≤ 20 cm) catheter

Recovery of kidney function · AKI patients receiving CKRT

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

CVVHD vs CVVH or CVVHDF

Death from any cause · AKI patients receiving CKRT

It is very uncertain whether CVVHD changes death from any cause compared with CVVH or CVVHDF (very low certainty).

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
RR 0.77 [0.42, 1.4]
4 studies · 229 participants
Very low

Long (> 20 cm) vs short (≤ 20 cm) catheter

Vascular access complications · AKI patients receiving CKRT

Long (> 20 cm) may leads to lower vascular access complications compared with short (≤ 20 cm) catheter (low certainty).

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
RR 0.38 [0.2, 0.72]
1 study · 94 participants
Low

Surface‐modified vs standard catheter

Circuit lifespan · AKI patients receiving CKRT

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 262 participants
Low

Surface‐modified vs standard catheter

Death from any cause at day 28 of · AKI patients receiving CKRT

It is very uncertain whether surface‐modified changes death from any cause at day 28 of compared with standard double‐lumen catheter with identical geometry and flow design (very low certainty).

1 finding from 1 review

Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal… 2021 · Cochrane Headline outcomes only
RR 1.08 [0.76, 1.53]
1 study · 236 participants
Very low