Signs or symptoms of pulpal disease · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth
Partial caries removal (single stage; residual dentinal caries… showed no clear difference in signs or symptoms of pulpal disease compared with complete caries removal (low certainty).
1 finding from 1 review
More advanced caries lesion detection · Primary teeth with occlusal surfaces
Pooled sensitivity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=23%; no GRADE rating was reported.
2 findings from 1 review
Sensitivity 0.672 [0.616, 0.725]
13 studies
GRADE not reported
Specificity 0.816 [0.793, 0.837]
13 studies
GRADE not reported
More advanced caries lesion detection · Permanent teeth with occlusal surfaces
Pooled specificity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=17%; no GRADE rating was reported.
2 findings from 1 review
Relative DOR by reference standard (LFpen, advanced, occlusal permanent) · Permanent teeth, occlusal surfaces, with suspected caries lesions
No significant reference-standard difference for LFpen at the advanced threshold (RDOR 0.96, 0.12 to 7.77).
1 finding from 1 review
Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Permanent teeth, occlusal surfaces, with suspected caries lesions
Fluorescence camera on occlusal surfaces of permanent teeth (initial-lesion threshold): accuracy similar among the three methods (very low inconsistency); heterogeneity I2=0%. Diagnostic accuracy was not formally graded (GRADE not used).
2 findings from 1 review
Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 6); accuracy similar among the three methods (very low inconsistency). Heterogeneity I2=0%. Numeric pooled values not…
Studies not reported
GRADE not reported
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of heterogeneity. 2013 All outcomesMore advanced (dentine/cavitated) caries lesions threshold · Laboratory (in vitro) and clinical (in vivo)
Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 6); pooled DOR for FC among the higher values, exceeding LFpen. Heterogeneity I2=17%. Numeric pooled values not…
Studies not reported
GRADE not reported
Diagnostic accuracy (pooled sensitivity, specificity, diagnostic odds ratio, summary-ROC AUC) · Primary teeth, occlusal surfaces, with suspected caries lesions
Laser fluorescence on occlusal surfaces of primary teeth (more advanced-lesion threshold): pooled DOR lowest for LF among the three methods; heterogeneity I2=23%. Diagnostic accuracy was not formally graded (GRADE not used).
2 findings from 1 review
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of heterogeneity. 2013 All outcomesMore advanced (dentine/cavitated) caries lesions threshold · Laboratory (in vitro) and clinical (in vivo)
Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 7); pooled DOR lowest for LF among the three methods. Heterogeneity I2=23%. Numeric pooled values not available in the…
Studies not reported
GRADE not reported
Pooled sensitivity, specificity, DOR, PLR, NLR and summary-ROC AUC reported qualitatively (Figure 7); accuracy similar among LF, LFpen and FC. Heterogeneity I2=75%. Numeric pooled values not available in the provided…
Studies not reported
GRADE not reported
Initial caries lesion detection · Primary teeth with occlusal surfaces
Pooled specificity was reported, but the numerical estimate is not stated in the supplied text or attached figures; I²=75%; no GRADE rating was reported.
2 findings from 1 review
Specificity 0.838 [0.810, 0.864]
14 studies
GRADE not reported
Sensitivity 0.622 [0.592, 0.651]
14 studies
GRADE not reported
Diagnostic accuracy (sensitivity, specificity) - not pooled · Permanent teeth (occlusal and smooth surfaces), with suspected caries lesions
Only 3 QLF studies were included, so no pooled estimate of QLF diagnostic accuracy could be calculated (evidence not graded).
1 finding from 1 review
Signs or symptoms of pulpal disease · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth
No dentinal caries removal (caries sealed under a preformed metal… showed no clear difference in signs or symptoms of pulpal disease compared with complete caries removal (moderate certainty).
1 finding from 1 review
Diagnostic accuracy (sensitivity, specificity) - not pooled · Permanent and primary teeth, smooth surfaces, with suspected caries lesions
Only 2 LF studies assessed smooth surfaces, so no pooled estimate was possible; both reported higher specificity than sensitivity (evidence not graded).
1 finding from 1 review
Restoration survival · Permanent posterior teeth with single-surface cavities
The pooled survival rate was 93% at 2 years.
6 findings from 1 review
Show 3 more findings
Restoration survival · Permanent posterior teeth with multiple-surface cavities
The pooled survival rate was 41% at 2 years.
3 findings from 1 review
Survival percentage 41 [18, 67]
1 study
GRADE not reported
Survival percentage 86 [59, 98]
3 studies
GRADE not reported
Survival percentage 77 [56, 92]
1 study
GRADE not reported
Restoration survival · Primary posterior teeth with single-surface cavities
The pooled survival rate was 95% at 1 year.
3 findings from 1 review
Restoration survival · Primary posterior teeth with multiple-surface cavities
The pooled survival rate was 62% at 2 years.
3 findings from 1 review
Tactile sensitivity (method a, ordinal scale) · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces
Potassium containing toothpaste (5% potassium nitrate) led to lower tactile sensitivity (method a, ordinal scale) compared with control toothpaste (without potassium); GRADE not reported.
1 finding from 1 review
MD -0.65 [-1.07, -0.23]
1 study
GRADE not reported
Thermal sensitivity · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces
Potassium containing toothpaste (5% potassium nitrate) led to lower thermal sensitivity compared with control toothpaste (without potassium); GRADE not reported.
1 finding from 1 review
MD -1.10 [-1.64, -0.55]
1 study
GRADE not reported
Subjective assessment of sensitivity · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces
Potassium containing toothpaste (5% potassium nitrate) showed no clear difference in subjective assessment of sensitivity compared with control toothpaste (without potassium); GRADE not reported.
1 finding from 1 review
Air blast sensitivity · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces
Potassium containing toothpaste (5% potassium nitrate) led to lower air blast sensitivity compared with control toothpaste (without potassium); GRADE not reported.
1 finding from 1 review
Tactile sensitivity (method b, continuous probe) · Healthy human adults (18 years or more) with dentine hypersensitivity from exposed root surfaces
Potassium containing toothpaste (5% potassium nitrate) led to higher tactile sensitivity (method b, continuous probe) compared with control toothpaste (without potassium); GRADE not reported.
1 finding from 1 review
Adverse events · People of any age with caries (including demineralisation in non-cavitated carious lesions); the caries may affect any single tooth…
1 finding from 1 review