Selective serotonin reuptake inhibitors vs placebo
Subjective sleep quality or quantity · adults with insomnia
1 finding from 1 review
- no estimate extracted3 studies · 135 participantsLow
Findings
What do systematic reviews say?
537 questions · 560 findings · 45 reviews · Common Mental Disorders
No studies found 105 · 18.8%GRADE not reported 8 · 1.4%Very low 170 · 30.4%Low 153 · 27.3%Moderate 94 · 16.8%High 30 · 5.4%
'Other' antidepressants vs placebo
Quality of sleep · adults with insomnia
1 finding from 1 review
- no estimate extracted3 studies · 370 participantsModerate
'Other' antidepressants vs placebo
Adverse events · adults with insomnia
1 finding from 1 review
- no estimate extracted2 studies · 217 participantsLow
'Other' antidepressants vs placebo
Sleep efficiency · adults with insomnia
1 finding from 1 review
- no estimate extracted2 studies · 169 participantsLow
Selective serotonin reuptake inhibitors vs placebo
Other subjective measures of sleep (total sleep time, sleep onset latency, nocturnal awakenings and subjective sleep efficiency) (PSQI) (at 12 weeks) · adults with insomnia
1 finding from 1 review
- no estimate extracted1 study · 27 participantsVery low
Selective serotonin reuptake inhibitors vs placebo
Adverse events (at 12 weeks) · adults with insomnia
1 finding from 1 review
- no estimate extracted1 study · 27 participantsVery low
Selective serotonin reuptake inhibitors vs placebo
PSG sleep outcomes (at 12 weeks) · adults with insomnia
1 finding from 1 review
- no estimate extracted1 study · 60 participantsVery low
Tricyclic antidepressants vs placebo
Quality of sleep · adults with insomnia
1 finding from 1 review
- no estimate extracted4 studies · 518 participantsModerate
Tricyclic antidepressants vs placebo
Adverse events (at 4, 6 or 12 weeks) · adults with insomnia
Tricyclic antidepressants showed no clear difference in adverse events (at 4, 6 or 12 weeks) compared with placebo (low certainty).
1 finding from 1 review
- RR 1.02 [0.86, 1.21]6 studies · 812 participantsLow
Tricyclic antidepressants vs placebo
Sleep onset latency ‐ not reported · adults with insomnia
1 finding from 1 review
- no estimate extracted4 studies · 510 participantsModerate
Tricyclic antidepressants vs placebo
Sleep efficiency · adults with insomnia
1 finding from 1 review
- no estimate extracted4 studies · 510 participantsModerate
Tricyclic antidepressants vs placebo
Total sleep time, next night; · adults with insomnia
1 finding from 1 review
- no estimate extracted4 studies · 510 participantsModerate
Tricylic antidepressant vs placebo
Change in depressive symptoms · chronic obstructive pulmonary disease (COPD) with depression
1 finding from 1 review
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extracted1 study · 30 participantsVery low
Selective serotonin reuptake inhibitors vs placebo
Change in quality of life · chronic obstructive pulmonary disease (COPD) with depression
1 finding from 1 review
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 148 participantsVery low
Selective serotonin reuptake inhibitors vs placebo
Change in dyspnoea score · chronic obstructive pulmonary disease (COPD) with depression
1 finding from 1 review
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extracted1 study · 23 participantsVery low
Selective serotonin reuptake inhibitors vs placebo
Lung function: FEV1 mL (change from baseline) · chronic obstructive pulmonary disease (COPD) with depression
1 finding from 1 review
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 148 participantsVery low
Selective serotonin reuptake inhibitors vs placebo
Change in exercise tolerance · chronic obstructive pulmonary disease (COPD) with depression
1 finding from 1 review
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 148 participantsVery low
Selective serotonin reuptake inhibitors vs placebo
Change in hospital utilisation ‐ not measured · chronic obstructive pulmonary disease (COPD) with depression
The review found no eligible studies for this question.
1 finding from 1 review
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Tricylic antidepressant vs placebo
Adverse events (disease‐related: all physical symptoms); · chronic obstructive pulmonary disease (COPD) with depression
1 finding from 1 review
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extracted1 study · 30 participantsVery low
Tricylic antidepressant vs placebo
Change in quality of life · chronic obstructive pulmonary disease (COPD) with depression
1 finding from 1 review
- Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes onlyno estimate extracted1 study · 30 participantsVery low