What do systematic reviews say?

Melatonin vs placebo

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 202 participants
  Very low

SSRI antidepressants vs tricyclic antidepressants (TCAs)

The review found no eligible studies for this question.

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

SSRI antidepressants vs tricyclic antidepressants (TCAs)

It is very uncertain whether SSRI antidepressants changes drop‐outs (12 weeks) compared with TCA (very low certainty).

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  RR 0.34 [0.11, 1.01]
  1 study · 25 participants
  Very low

SSRI antidepressants vs tricyclic antidepressants (TCAs)

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 141 participants
  Moderate

SSRI antidepressants vs tricyclic antidepressants (TCAs)

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Very low

Atypical vs Typical antipsychotics

Atypical showed no clear difference in drop‐outs (6 to 54 weeks) compared with typical antipsychotic medications (low certainty).

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  RR 1.31 [0.63, 2.69]
  2 studies · 144 participants
  Low

Atypical vs Typical antipsychotics

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 211 participants
  Moderate

Atypical vs Typical antipsychotics

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 141 participants
  Moderate

Metformin vs placebo

The review found no eligible studies for this question.

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metformin vs placebo

Metformin showed no clear difference in drop‐outs (12 to 14 weeks) compared with placebo (moderate certainty).

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  RR 1.22 [0.09, 16.35]
  3 studies · 158 participants
  Moderate

Metformin vs placebo

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 173 participants
  Moderate
• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 91 participants
  High

Metformin vs placebo

• Interventions for preventing type 2 diabetes in adults with mental disorders in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 264 participants
  High

Mindfulness vs no treatment or waiting list

The review found no eligible studies for this question.

• Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mindfulness vs no treatment or waiting list

The review found no eligible studies for this question.

• Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mindfulness vs no treatment or waiting list

The review found no eligible studies for this question.

• Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mindfulness vs no treatment or waiting list

• Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 255 participants
  Very low

Mindfulness vs no treatment or waiting list

• Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 250 participants
  Low

Mindfulness vs no treatment or waiting list

• Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 233 participants
  Low

Mindfulness vs no treatment or waiting list

• Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 91 participants
  Very low

Mindfulness vs no treatment or waiting list

• Mindfulness‐based psychological interventions for improving mental well‐being in medical students and junior doctors 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 79 participants
  Very low