Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,355 questions · 2,459 findings · 279 reviews

No studies found 556 · 22.6%GRADE not reported 490 · 19.9%Very low 593 · 24.1%Low 479 · 19.5%Moderate 243 · 9.9%High 98 · 4%

Indirect bonding using flowable composite adhesive (Opal Bond MV) vs Direct bonding (conventional, Transbond XT)

White spot lesion formation (QLF: fluorescence loss, lesion area) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)

A single RCT found indirect bonding with flowable composite reduced white spot lesion formation versus direct bonding (ungraded).

1 finding from 1 review

High‐frequency chest wall oscillation plus fibrobronchoscope alveolar lavage vs fibrobronchoscope alveolar lavage alone

All‐cause mortality · people with severe pneumonia and receiving mechanical ventilation

It is very uncertain whether high‐frequency chest wall oscillation plus fibrobronchoscope… changes mortality compared with fibrobronchoscope alveolar lavage alone (very low certainty).

1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Marginal deterioration of the restoration and fracture of the remaining tooth tissue · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Restoration survival · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Economic data: direct costs of materials and any reported associated indirect costs · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…

The review found no eligible studies for this question.

1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Adverse effects · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…

The review found no eligible studies for this question.

1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Secondary caries · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…

The review found no eligible studies for this question.

1 finding from 1 review

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Post‐insertion sensitivity or pain assessed by a validated pain scale · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
1 finding from 1 review

Intervention not reported

Finding 20. There are some considerations for designing interventions that promote physical activity for bipolar disorder. These include sequencing multicomponent lifestyle changes, technology, incentives, and health promotion strategies that are ... · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

Intervention not reported

Finding 13. Healthcare providers and policymakers highlighted the need for adequate equipment, infrastructure and maintenance both on the provider side and the patient side but described how these needs were not always met. They described challeng...
1 finding from 1 review

Intervention not reported

Finding 6. Patients, caregivers, and providers described a number of privacy and confidentiality issues when services were provided at home. These included the increased privacy of being able to exercise at home but also the loss of privacy when e...

The review found no eligible studies for this question.

1 finding from 1 review

Resin-based fissure sealant vs Fluoride varnish

Safety of sealants and fluoride varnishes (adverse events) · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review

Analysis 1 ‐ Oxidised regenerated cellulose vs no treatment at laparotomy

Incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy · women having gynaecological surgery

It is very uncertain whether analysis 2 ‐ Oxidised regenerated cellulose changes incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy compared with no treatment at laparotomy (very low certainty).

1 finding from 1 review

Analysis 1 ‐ Oxidised regenerated cellulose vs no treatment at laparotomy

Incidence of adhesions ‐ re‐formation (or mixture) Incidence at second‐look laparoscopy · women having gynaecological surgery

Analysis 2 ‐ Oxidised regenerated cellulose may leads to lower incidence of adhesions ‐ re‐formation (or mixture) Incidence at… compared with no treatment at laparotomy (low certainty).

1 finding from 1 review