Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

364 questions · 389 findings · 54 reviews

No studies found 95 · 24.4%GRADE not reported 40 · 10.3%Very low 45 · 11.6%Low 126 · 32.4%Moderate 76 · 19.5%High 7 · 1.8%

An extended NVP regimen administered to infants for 14 weeks vs sdNVP plus ZDV (1 week)

Infants with Probably Related Severe Adverse Events · Breastfeeding infants of HIV‐infected mothers

It is very uncertain whether an extended NVP regimen administered to infants for 14 weeks changes infants with Probably Related Severe Adverse Events11 compared with sdNVP plus ZDV (1week) (very low certainty).

1 finding from 1 review

An extended NVP plus ZDV dual regimen administered to infants for 14 weeks vs sdNVP plus ZDV (1 week)

HIV Transmission at 9 months among those whose HIV diagnostic testing was negative within 48 hours of birth · Breastfeeding infants of HIV‐infected mothers

An extended NVP plus ZDV regimen administered to infants for 14 weeks probably leads to lower HIV Transmission at 9 months among those whose HIV diagnostic… compared with sdNVP plus ZDV (1 week) (moderate certainty).

1 finding from 1 review

Summary of findings ‐ Nipple stimulation (suckling) vs no treatment (comparison 1)

Maternal death · nipple stimulation (suckling) for preventing postpartum haemorrhage in the third stage of labour.

It is very uncertain whether summary of findings ‐ Nipple stimulation (suckling) changes maternal death compared with no treatment (comparison 1) (very low certainty).

1 finding from 1 review

Summary of findings ‐ Nipple stimulation (suckling) vs no treatment (comparison 1)

Frequency of PPH ≥ 500 mL · nipple stimulation (suckling) for preventing postpartum haemorrhage in the third stage of labour.

Summary of findings ‐ Nipple stimulation (suckling) showed no clear difference in frequency of PPH ≥ 500 mL compared with no treatment (comparison 1) (moderate certainty).

1 finding from 1 review

Summary of findings ‐ Nipple stimulation (suckling) vs no treatment (comparison 1)

Retained placenta · nipple stimulation (suckling) for preventing postpartum haemorrhage in the third stage of labour.

It is very uncertain whether summary of findings ‐ Nipple stimulation (suckling) changes retained placenta compared with no treatment (comparison 1) (very low certainty).

1 finding from 1 review