Findings

What do systematic reviews say?

4,730 questions · 18,059 findings · 1,282 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 4,360 · 24.1%GRADE not reported 2,529 · 14%Very low 4,641 · 25.7%Low 4,007 · 22.2%Moderate 2,057 · 11.4%High 465 · 2.6%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Naproxen vs placebo

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Naproxen vs placebo

Relief of pain

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Low

Naproxen vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale)

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Low

Naproxen vs placebo

Additional analgesia required (escape analgesia)

Naproxen showed no clear difference in need for additional analgesia (self‐recorded) compared with placebo (low certainty).

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
OR 0.29 [0.05, 1.8]
1 study · 33 participants
Low

Naproxen vs placebo

Gastrointestinal effects

Naproxen showed no clear difference in side effects: gastrointestinal symptoms compared with placebo (low certainty).

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
OR 2.11 [0.18, 25.17]
1 study · 33 participants
Low

Intervention not reported

Percentage days bleeding or spotting (questionnaire)

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 118 participants
Low

Intervention not reported

Adverse events or side effects

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Menstrual blood loss

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Duration of bleeding Median number of bleed days (diary)

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 168 participants
Low

Intervention not reported

Side effects: gastrointestinal disorders, headache, breast tenderness, musculoskeletal disorders

The intervention showed no clear difference in side effects: gastrointestinal disorders, headache, breast… (low certainty).

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
OR 1 [0.49, 2.02]
1 study · 168 participants
Low

Intervention not reported

Mifepristone vs vitamin B

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Duration of bleeding % spotting and bleeding days

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Very low

Intervention not reported

Naproxen vs estradiol

The review found no eligible studies for this question.

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Duration of bleeding Median number of bleeding and spotting days (diary)

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 106 participants
Very low

Intervention not reported

Side effects: gastroesophageal reflux

It is very uncertain whether the intervention changes side effects: gastroesophageal reflux (very low certainty).

1 finding from 1 review

Interventions to prevent or treat heavy menstrual bleeding or pain associated with intrauterine‐device use 2022 · Cochrane Headline outcomes only
OR 3.22 [0.13, 81.19]
1 study · 86 participants
Very low

Antidepressants vs placebo

Gambling symptom severity · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 225 participants
Very low

Opioid antagonists vs placebo

Gambling expenditure ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioid antagonists vs placebo

Gambling frequency ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioid antagonists vs placebo

Time spent gambling ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioid antagonists vs placebo

Depressive symptoms · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 77 participants
Low