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What do systematic reviews say?

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Evidence found and GRADE certainty

4,695 questions · 4,979 findings · 433 reviews

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No studies found 998 · 20%GRADE not reported 1,140 · 22.9%Very low 1,024 · 20.6%Low 1,029 · 20.7%Moderate 636 · 12.8%High 152 · 3.1%

Class III antiarrhythmics vs control

Recurrence of atrial tachyarrhythmias · Human trial participants undergoing ablation for atrial fibrillation

Class III antiarrhythmics showed no clear difference in recurrence of atrial tachyarrhythmias compared with control (low certainty).

1 finding from 1 review

Class III antiarrhythmics vs control

Adverse events: thromboembolic events · Human trial participants undergoing ablation for atrial fibrillation

It is very uncertain whether class III antiarrhythmics changes adverse events: thromboembolic events compared with control (very low certainty).

1 finding from 1 review

Class I and/or III antiarrhythmics vs control

Recurrence of atrial tachyarrhythmias · Human trial participants undergoing ablation for atrial fibrillation

Class I and/or III antiarrhythmics probably leads to lower recurrence of atrial tachyarrhythmias compared with control (moderate certainty).

1 finding from 1 review

Class I and/or III antiarrhythmics vs control

Adverse events: thromboembolic events · Human trial participants undergoing ablation for atrial fibrillation

It is very uncertain whether class I and/or III antiarrhythmics changes adverse events: thromboembolic events compared with control (very low certainty).

1 finding from 1 review

Intranasal steroid spray vs placebo

Adverse event: systemic corticosteroid side effects · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether topical (intranasal) steroids changes adverse event: systemic corticosteroid side effects compared with placebo (very low certainty).

1 finding from 1 review