Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

483 questions · 519 findings · 42 reviews · Headline outcomes only

No studies found 136 · 26.2%GRADE not reported 9 · 1.7%Very low 136 · 26.2%Low 150 · 28.9%Moderate 68 · 13.1%High 20 · 3.9%

INTEGRATED MODELS OF CARE vs usual care

Substance use: any change ‐ Drug use (not in remission) · people with both severe mental illness and substance misuse

Integrated models of care showed no clear difference in substance use: any change ‐ Drug use (not in remission) compared with standard care (low certainty).

1 finding from 1 review

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).

1 finding from 1 review

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Adverse event: Death · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in adverse event: Death compared with standard care (low certainty).

1 finding from 1 review

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Relapse · people with both severe mental illness and substance misuse

It is very uncertain whether cognitive behavioural therapy + motivational interviewing changes relapse:* Relapse at 3 months after 9 months of treatment compared with standard care (very low certainty).

1 finding from 1 review