Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

510 questions · 533 findings · 60 reviews

No studies found 153 · 28.7%GRADE not reported 18 · 3.4%Very low 134 · 25.1%Low 123 · 23.1%Moderate 80 · 15%High 25 · 4.7%

Corticosteroids vs placebo

Histological improvement (dichotomous) · active EoE patients

Corticosteroids leads to higher histological improvement (dichotomous) compared with placebo (high certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Clinical improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes clinical improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Histological improvement at 4 weeks (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes histological improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Endoscopic improvement (dichotomous) · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes endoscopic improvement at 4 weeks (dichotomous) compared with oral prednisone (very low certainty).

1 finding from 1 review

Swallowed fluticasone vs prednisone

Withdrawals due to adverse events · active EoE pediatric patients

It is very uncertain whether swallowed fluticasone changes withdrawals due to adverse events at 4 weeks compared with oral prednisone (very low certainty).

1 finding from 1 review