Miscarriage · Women with polycystic ovary syndrome, oligo amenorrhoea and subfertility
Metformin showed no clear difference in miscarriage rate per woman compared with placebo or no treatment (low certainty).
1 finding from 1 review
Live birth rate per woman · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate showed no clear difference in live birth rate per woman compared with clomiphene citrate alone (low certainty).
Gastrointestinal adverse events · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate probably leads to higher adverse events (gastrointestinal) per woman compared with clomiphene citrate alone (moderate certainty).
Clinical pregnancy rate · women with polycystic ovary syndrome
Metformin combined with clomiphene citrate probably leads to higher clinical pregnancy rate per woman compared with clomiphene citrate alone (moderate certainty).
Hypertensive disorders of pregnancy · pregnant women with diabetes
1 finding from 1 review
Adiposity (infant) · infants of pregnant women with diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neurosensory disability · infants of pregnant women with diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Caesarean section · pregnant women with diabetes
It is very uncertain whether CSII changes caesarean section compared with MDI: maternal outcomes (very low certainty).
1 finding from 1 review
Development of type 2 diabetes · pregnant women with diabetes
1 finding from 1 review
Perineal trauma · pregnant women with diabetes
1 finding from 1 review
Return to pre‐pregnancy weight · pregnant women with diabetes
1 finding from 1 review
Postnatal depression · pregnant women with diabetes
1 finding from 1 review
Induction of labour · pregnant women with diabetes
1 finding from 1 review
Large‐for‐gestational age · infants of pregnant women with diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Neonatal hypoglycaemia · infants of pregnant women with diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
All‐cause mortality
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Diabetes‐related morbidity
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Health‐related quality of life
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Patient satisfaction
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Adverse events: a. mild hypoglycaemia (episodes per participant)
1 finding from 1 review