Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

473 questions · 480 findings · 60 reviews · Headline outcomes only

No studies found 100 · 20.8%GRADE not reported 3 · 0.6%Very low 104 · 21.7%Low 129 · 26.9%Moderate 106 · 22.1%High 38 · 7.9%

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

Participant‐reported improvement of hirsutism 4‐point Likert scale · women with hirsutism

Finasteride 5 mg showed no clear difference in participant‐reported improvement of hirsutism 4‐point Likert scale compared with flutamide 250 mg once to b.i.d. (low certainty).

1 finding from 1 review

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

Proportion of participants who reported an adverse event · women with hirsutism

It is very uncertain whether finasteride 5 mg changes proportion of participants who reported an adverse event compared with flutamide 250 mg once to b.i.d. (very low certainty).

1 finding from 1 review