Findings

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Evidence found and GRADE certainty

4,749 questions · 14,273 findings · 834 reviews

No studies found 3,655 · 25.6%GRADE not reported 2,115 · 14.8%Very low 3,646 · 25.5%Low 3,034 · 21.3%Moderate 1,503 · 10.5%High 320 · 2.2%

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ARP with xenograft (bone graft) vs Extraction alone

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes changes in vertical height of alveolar ridge (mm) compared with extraction alone (very low certainty).

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with demineralised bone matrix, single particle size changes changes in vertical height of alveolar ridge (mm) compared with ARP with demineralised bone matrix, multiple particle size (very low certainty).

1 finding from 1 review

Selective carious tissue removal (selective excavation, SE) vs Stepwise carious tissue removal (SW)

Efficiency, costs or cost-effectiveness · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
1 finding from 1 review

ARP with xenograft (bone graft) vs Extraction alone

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with xenograft (bone graft) changes implant failure rate compared with extraction alone (very low certainty).

1 finding from 1 review

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

Incidence of eruption of the PDC into the mouth · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

It is very uncertain whether extraction of the primary (baby) canine (single primary tooth… changes incidence of eruption of the PDC into the mouth compared with no extraction (non-intervention control) (very low certainty).

1 finding from 1 review

Sealing using sealant materials vs Selective carious tissue removal (selective excavation, SE)

Lesion progression · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…
1 finding from 1 review
  • Interventions for treating cavitated or dentine carious lesions 2021 · Cochrane All outcomes
    Cavitated lesions, primary dentition
    Lesion progression reported narratively: Dias 2018 1/27 sealed vs 1/21 SE at 24 months; Hesse 2014 0/17 sealed vs 0/17 SE at 18 months; not pooled and not GRADE-rated.
    2 studies
    GRADE not reported

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with allograft plus synthetic cell-binding peptide P-15 vs ARP with allograft without P-15

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with allograft plus synthetic cell-binding peptide P-15 changes changes in bucco-lingual/palatal width of alveolar ridge (mm) compared with ARP with allograft without P-15 (very low certainty).

1 finding from 1 review

Selective carious tissue removal (selective excavation, SE) vs Stepwise carious tissue removal (SW)

Failure of therapy · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

Selective carious tissue removal (selective excavation, SE) probably leads to higher failure of therapy compared with stepwise carious tissue removal (SW) (moderate certainty).

2 findings from 1 review

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Costs and cost‐effectiveness · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Reported improvement in the position of the ectopic canine measured from radiographs · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Patient‐reported outcome measures (PROMs) · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

ARP with alloplast vs Extraction alone

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

ARP with allograft (bone graft) vs ARP with xenograft

Changes in bucco-lingual/palatal width of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with allograft changes changes in bucco-lingual/palatal width of alveolar ridge (mm) compared with ARP with xenograft (very low certainty).

1 finding from 1 review

ARP with alloplast vs ARP with xenograft

Changes in vertical height of alveolar ridge (mm) · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

It is very uncertain whether ARP with alloplast changes changes in vertical height of alveolar ridge (mm) compared with ARP with xenograft (very low certainty).

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Aesthetic outcomes of future prosthodontic rehabilitation · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

Any other adverse effects of the interventions, such as gingival disease and demineralisation · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

ARP with demineralised bone matrix, single particle size vs ARP with demineralised bone matrix, multiple particle size

Implant failure rate · Adults aged 18 years or older, in good general health (including well-controlled systemic disease), requiring extraction of one or more…

The review found no eligible studies for this question.

1 finding from 1 review