Major bleeding · patients with < 30 days' limb ischaemiaa
It is very uncertain whether intra‐arterial delivery changes major bleeding (up to 6 months) compared with intravenous delivery (very low certainty).
1 finding from 1 review
Amputation · patients with < 42 days' limb ischaemiaa
1 finding from 1 review
Mean relative percentage in quality of life score at 3 months · children with cystic fibrosis
Dornase alfa daily showed no clear difference in mean relative percentage in quality of life score at 3 months compared with alternate days (low certainty).
1 finding from 1 review
Pulmonary exacerbations · children with cystic fibrosis
1 finding from 1 review
FEV1 · children with cystic fibrosis
Dornase alfa daily showed no clear difference in mean relative percentage change in FEV1 (L) at 3 months compared with alternate days (low certainty).
1 finding from 1 review
Mean relative percentage in FVC (L) at 3 months · children with cystic fibrosis
Dornase alfa daily showed no clear difference in mean relative percentage in FVC (L) at 3 months compared with alternate days (low certainty).
1 finding from 1 review
Intervention not reported
Need for surgical closure of PDA (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention probably leads to lower need for surgical closure of PDA (during hospital stay) (moderate certainty).
1 finding from 1 review
Intervention not reported
IVH grade III to IV (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention showed no clear difference in IVH grade III to IV (during hospital stay) (moderate certainty).
1 finding from 1 review
Intervention not reported
NEC (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention showed no clear difference in NEC (during hospital stay) (moderate certainty).
1 finding from 1 review
Intervention not reported
Gastrointestinal haemorrhage (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention may leads to higher gastrointestinal haemorrhage (during hospital stay) (low certainty).
1 finding from 1 review
Intervention not reported
Oliguria (during ibuprofen treatment) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention leads to higher oliguria (during ibuprofen treatment) (high certainty).
1 finding from 1 review
Intervention not reported
Serum creatinine levels (mg/dL) (after treatment) Normal values for male and female newborns (17.7 to 88.4 µmol/L) (0.23 to 1.16 mg/dL) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
1 finding from 1 review
Intervention not reported
Gastrointestinal haemorrhage (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention may leads to higher gastrointestinal haemorrhage (during hospital stay) (low certainty).
1 finding from 1 review
Complete cure, at least 3 months after the end of treatment · People with American cutaneous leishmaniasis
Thermotherapy one session (at 50 ºC for 30 seconds) leads to lower complete cure, at least 3 months after the end of treatment compared with meglumine antimoniate (20 mg Sb5/kg/day (high certainty).
1 finding from 1 review
Adverse effects · People with American cutaneous leishmaniasis
1 finding from 1 review
Recurrence ‐ not measured · People with American cutaneous leishmaniasis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Maternal outcomes · pregnant women, or those within 42 days of delivery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Systolic BP ≥ 150 mmHg · pregnant women, or those within 42 days of delivery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Maternal death · pregnant women, or those within 42 days of delivery
Technique of BP measurement: CRADLE intervention showed no clear difference in maternal death compared with usual care (low certainty).
1 finding from 1 review
Pre‐eclampsia · pregnant women, or those within 42 days of delivery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found