Mortality at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy probably leads to lower mortality at 6 months compared with medical treatment only (moderate certainty).
1 finding from 1 review
Mortality at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy leads to lower mortality at 12 months compared with medical treatment only (high certainty).
1 finding from 1 review
'Unfavorable outcome' as per original Cochrane protocol at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy may leads to higher 'Unfavorable outcome' as per original Cochrane protocol at 6 months compared with medical treatment only (low certainty).
1 finding from 1 review
'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy showed no clear difference in 'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months compared with medical treatment only (high certainty).
1 finding from 1 review
Changes in ICP from randomization up to 48 h · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
Decompressive craniectomy showed no clear difference in changes in ICP from randomization up to 48 h compared with medical treatment only (moderate certainty).
1 finding from 1 review
Adverse events assessed in various ways, up to 24 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…
1 finding from 1 review
Overall survival ( · people with HGG
Anti‐angiogenic therapy showed no clear difference in overall survival ( compared with no anti‐angiogenic therapy (high certainty).
4 findings from 1 review
HR 0.95 [0.88, 1.02]
11 studies · 3743 participants
High
HR 0.93 [0.86, 1.02]
8 studies · 2833 participants
High
HR 0.99 [0.85, 1.16]
3 studies · 910 participants
Moderate
Show 1 more finding
Progression‐free survival · people with HGG
Anti‐angiogenic therapy leads to lower progression‐free survival ( compared with no anti‐angiogenic therapy (high certainty).
4 findings from 1 review
HR 0.73 [0.68, 0.79]
10 studies · 3595 participants
High
HR 0.75 [0.69, 0.82]
8 studies · 2833 participants
High
HR 0.64 [0.54, 0.76]
2 studies · 762 participants
Moderate
Show 1 more finding
Any perinatal death after randomisation · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound probably leads to lower any perinatal death after randomisation compared with no Doppler ultrasound (moderate certainty).
1 finding from 1 review
Serious neonatal morbidity · pregnant women at increased risk of fetal complications
1 finding from 1 review
Stillbirth · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound showed no clear difference in stillbirth compared with no Doppler ultrasound (low certainty).
1 finding from 1 review
Apgar score less than 7 at 5 minutes · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound showed no clear difference in apgar < 7 at 5 minutes compared with no Doppler ultrasound (low certainty).
1 finding from 1 review
Caesarean section · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound probably leads to lower caesarean section (elective and emergency) compared with no Doppler ultrasound (moderate certainty).
1 finding from 1 review
Induction of labour · pregnant women at increased risk of fetal complications
Umbilical artery Doppler ultrasound probably leads to lower induction of labour compared with no Doppler ultrasound (moderate certainty).
1 finding from 1 review
Neurodevelopmental outcomes · pregnant women at increased risk of fetal complications
1 finding from 1 review
Intervention not reported
Overall survival · people with non‐rhabdomyosarcoma soft tissue sarcoma
The intervention showed no clear difference in overall survival (high certainty).
1 finding from 1 review
Intervention not reported
Treatment‐related mortality · people with non‐rhabdomyosarcoma soft tissue sarcoma
1 finding from 1 review
Intervention not reported
Disease‐free survival · people with non‐rhabdomyosarcoma soft tissue sarcoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Progression‐free survival · people with non‐rhabdomyosarcoma soft tissue sarcoma
The intervention showed no clear difference in progression‐free survival (high certainty).
1 finding from 1 review
Intervention not reported
Non‐hematologic toxicity grade 3 to 4 · people with non‐rhabdomyosarcoma soft tissue sarcoma
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found