Findings

What do systematic reviews say?

4,345 questions · 4,525 findings · 483 reviews

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No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Laparoscopic vs open surgery

QoL · patients with sigmoid diverticulitis

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
no estimate extracted
2011 participants
Low

Laparoscopic vs open surgery

Recurrent diverticulitis rate ( · patients with sigmoid diverticulitis

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
no estimate extracted
2010 participants
Very low

Laparoscopic vs open surgery

30‐Day postoperative mortality · patients with sigmoid diverticulitis

Laparoscopic showed no clear difference in 30‐Day postoperative mortality compared with open surgery (low certainty).

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
RR 0.24 [0.03, 2.07]
3 studies · 360 participants
Low

Laparoscopic vs open surgery

Overall rate of surgical complications · patients with sigmoid diverticulitis

Laparoscopic showed no clear difference in overall surgical complications ( compared with open surgery (low certainty).

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
RR 0.84 [0.6, 1.19]
3 studies · 360 participants
Low

Laparoscopic vs open surgery

Early overall morbidity (30 postoperative days) · patients with sigmoid diverticulitis

It is very uncertain whether laparoscopic changes early overall morbidity (30 postoperative days) compared with open surgery (very low certainty).

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
RR 1.46 [0.51, 4.2]
1 study · 113 participants
Very low

Laparoscopic vs open surgery

Late overall morbidity (after the first 30 postoperative days: within 6 months) · patients with sigmoid diverticulitis

It is very uncertain whether laparoscopic changes late overall morbidity (after the first 30 postoperative days:… compared with open surgery (very low certainty).

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
RR 0.6 [0.26, 1.38]
1 study · 93 participants
Very low

Laparoscopic vs open surgery

Late overall mortality (after the first 30 postoperative days) · patients with sigmoid diverticulitis

It is very uncertain whether laparoscopic changes late overall mortality (after the first 30 postoperative days) compared with open surgery (very low certainty).

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
RR 2.04 [0.19, 21.77]
1 study · 93 participants
Very low

Laparoscopic vs open surgery

Major complications · patients with sigmoid diverticulitis

Laparoscopic showed no clear difference in major complications ( compared with open surgery (low certainty).

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
RR 0.74 [0.43, 1.25]
3 studies · 360 participants
Low

Laparoscopic vs open surgery

Minor complications (3 to 6 weeks · patients with sigmoid diverticulitis

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 360 participants
Very low

Laparoscopic vs open surgery

Operating time · patients with sigmoid diverticulitis

1 finding from 1 review

Laparoscopic versus open resection for sigmoid diverticulitis 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 360 participants
Low

Summary of findings: liposomal bupivacaine vs placebo

Cumulative pain score from the end of operation (0 hours) to 72 hours (NRS 0 to 10) · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 189 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Time to first postoperative opioid dose over initial 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

The review found no eligible studies for this question.

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: liposomal bupivacaine vs bupivacaine

Total postoperative opioid consumption over first 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 134 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Percentage of participants not requiring postoperative opioids over initial 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 134 participants
Very low

Summary of findings: liposomal bupivacaine vs placebo

Serious adverse events · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 382 participants
Low

Summary of findings: liposomal bupivacaine vs placebo

Time to first postoperative opioid dose over initial 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 382 participants
Low

Summary of findings: liposomal bupivacaine vs placebo

Total postoperative opioid consumption over first 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 189 participants
Very low

Summary of findings: liposomal bupivacaine vs placebo

Percentage of participants not requiring postoperative opioids over initial 72 hours · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 382 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Cumulative pain score from the end of operation (0 hours) to 72 hours (NRS 0 to 10) · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 379 participants
Very low

Summary of findings: liposomal bupivacaine vs bupivacaine

Serious adverse events · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 583 participants
Moderate