Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

462 questions · 474 findings · 56 reviews · Eyes and Vision

No studies found 147 · 31%GRADE not reported 15 · 3.2%Very low 89 · 18.8%Low 157 · 33.1%Moderate 52 · 11%High 14 · 3%

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ wound leak ‐ primary trabeculectomy · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ wound leak ‐ primary trabeculectomy compared with control (low certainty).

1 finding from 1 review

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ shallow anterior chamber ‐ primary trabeculectomy · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil showed no clear difference in complications ‐ shallow anterior chamber ‐ primary trabeculectomy compared with control (low certainty).

1 finding from 1 review

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ epithelial toxicity ‐ primary trabeculectomy · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil may leads to higher complications ‐ epithelial toxicity ‐ primary trabeculectomy compared with control (low certainty).

1 finding from 1 review