Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

407 questions · 412 findings · 45 reviews · Headline outcomes only

No studies found 137 · 33.3%GRADE not reported 8 · 1.9%Very low 129 · 31.3%Low 88 · 21.4%Moderate 47 · 11.4%High 3 · 0.7%

Vaginal preparation with antiseptic solution vs control (no preparation or saline preparation)

Composite wound complication or endometritis · pregnant women undergoing caesarean section

Vaginal preparation with antiseptic solution may leads to lower composite wound complication or endometritis compared with control (no preparation or saline preparation) (low certainty).

1 finding from 1 review

Magnesium sulphate vs hypertonic saline

Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured 25 to 48 hoursafter treatment · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with hypertonic saline (very low certainty).

1 finding from 1 review

Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine

Length of hospital stay · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate + epinephrine changes duration of hospital stay compared with no treatment or normal saline + epinephrine (very low certainty).

1 finding from 1 review

Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine

Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured at 0 to 24 hoursafter treatment · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate + epinephrine changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with no treatment or normal saline + epinephrine (very low certainty).

1 finding from 1 review

Magnesium sulphate + epinephrine vs no treatment or normal saline + epinephrine

Clinical severity score (CSS) (RDAI score; range 0 to 17; higher = poorer outcomes) measured 25 to 48 hoursafter treatment · children up to 12 months old with acute bronchiolitis

It is very uncertain whether magnesium sulphate + epinephrine changes clinical severity score (CSS) (RDAI score; range 0 to 17; higher =… compared with no treatment or normal saline + epinephrine (very low certainty).

1 finding from 1 review

Topical phenytoin vs saline dressing

Ulcer healing · ulceration and other skin changes caused by nerve damage in leprosy
2 findings from 1 review