Droperidol leads to higher tranquillisation or asleep: tranquillised/sleep ‐ by around 30 minutes compared with placebo (high certainty).
Droperidol leads to lower global state: use of additional medication ‐ by 60 minutes after… compared with placebo (high certainty).
Droperidol showed no clear difference in adverse effects ‐ cardiovascular ‐ arrhythmia compared with placebo (moderate certainty).
Droperidol showed no clear difference in adverse effects ‐ respiratory ‐ airway obstruction compared with placebo (low certainty).
Droperidol showed no clear difference in service use: person able to be discharged home compared with placebo (high certainty).
VALPROATE + ANTIPSYCHOTICS may leads to higher clinically significant response: important change As defined by each… compared with ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone (low certainty).
It is very uncertain whether VALPROATE + ANTIPSYCHOTICS changes leaving the study early: Acceptability of treatment Leaving the… compared with ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone (very low certainty).
VALPROATE + ANTIPSYCHOTICS showed no clear difference in leaving the study early: Overall tolerability Leaving the study… compared with ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone (low certainty).
VALPROATE + ANTIPSYCHOTICS may leads to higher adverse events: Sedation Number of participants with… compared with ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone (low certainty).
VALPROATE + ANTIPSYCHOTICS showed no clear difference in adverse events: Weight gain Number of participants with weight gain compared with ANTIPSYCHOTICS + PLACEBO or ANTIPSYCHOTICS alone (low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
It is very uncertain whether RISPERIDONE DEPOT changes leaving the study early: Any reason ‐ all doses risperidone depot ‐… compared with PLACEBO (very low certainty).
It is very uncertain whether RISPERIDONE DEPOT changes adverse events: General: Severe adverse event ‐ any dose risperidone… compared with PLACEBO (very low certainty).
It is very uncertain whether RISPERIDONE DEPOT changes adverse events: Specific: Weight gain ‐ all doses of depot… compared with PLACEBO (very low certainty).