Pulp exposure during caries removal · Children with dentine caries in primary and permanent teeth
Partial caries removal was reported to reduce pulp-exposure risk by 77% versus complete caries removal (RR 0.23; ungraded).
1 finding from 1 review
RR 0.23 [0.08, 0.69]
2 studies
GRADE not reported
Pulp exposure during caries removal · Children (3-11 years) with symptomless, vital dentine caries in primary molars
Partial caries removal reduced the reported risk of pulp exposure versus complete caries removal in primary teeth (RR 0.24; ungraded).
1 finding from 1 review
RR 0.24 [0.06, 0.90]
262 participants
GRADE not reported
Pulpal disease (signs/symptoms of pulp necrosis) · Children with dentine caries in primary and permanent teeth
The reported estimate did not show a clear difference in pulpal disease after partial versus complete caries removal (ungraded).
1 finding from 1 review
RR 0.27 [0.05, 1.60]
3 studies
GRADE not reported
Implant failure · Patients with insufficient bone below the maxillary sinus requiring dental implants
One-stage augmentation (implants placed simultaneously) showed no clear difference in implant failure compared with two-stage augmentation (delayed implant placement); GRADE not reported.
1 finding from 1 review
Prosthesis failure · Patients with insufficient bone below the maxillary sinus requiring dental implants
One-stage augmentation (implants placed simultaneously) showed no clear difference in prosthesis failure compared with two-stage augmentation (delayed implant placement); GRADE not reported.
1 finding from 1 review
Complications · Patients with insufficient bone below the maxillary sinus requiring dental implants
One-stage augmentation (implants placed simultaneously) showed no clear difference in complications compared with two-stage augmentation (delayed implant placement); GRADE not reported.
1 finding from 1 review
Prosthesis failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site led to lower prosthesis failure compared with no augmentation; GRADE not reported.
1 finding from 1 review
In total two implants were lost in the autogenous bone group, whereas no complications or failures occurred in the non-augmented control group; underpowered, no statistically significant difference (Chen 2005b).
1 study · 26 participants
GRADE not reported
Implant failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site led to lower implant failure compared with no augmentation; GRADE not reported.
1 finding from 1 review
Major complications at the implant/donor site · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site led to lower major complications at the implant/donor site compared with no augmentation; GRADE not reported.
1 finding from 1 review
Two complications occurred in the group treated with autogenous bone (one abscess that determined the early failure of the implant and one wound dehiscence); none in the control group.
1 study · 26 participants
GRADE not reported
Time to resolution of first ulcer (days) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Prednisone (oral, commencing 25 mg with phased dose reduction over 2… led to lower time to resolution of first ulcer (days) compared with placebo; GRADE not reported.
1 finding from 1 review
Time to resolution of first ulcer (days) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Prednisone (oral, commencing 25 mg with phased dose reduction over 2… led to lower time to resolution of first ulcer (days) compared with montelukast (leukotriene receptor antagonist); GRADE not reported.
1 finding from 1 review
Total number of new lesions over 2-month treatment period · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Prednisone (oral, commencing 25 mg with phased dose reduction over 2… led to lower total number of new lesions over 2-month treatment period compared with placebo; GRADE not reported.
1 finding from 1 review
Days to resolution of pain / epithelialization; number of aphthae per month · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Femiano 2003 (high risk of bias) reports days to resolution of pain and days to epithelialization of aphthae at 1 month, and number of aphthae per month after the first and second months; data presented as…
1 study · 20 participants
GRADE not reported
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Total number of new lesions over 2-month treatment period · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
Prednisone (oral, commencing 25 mg with phased dose reduction over 2… showed no clear difference in total number of new lesions over 2-month treatment period compared with montelukast (leukotriene receptor antagonist); GRADE not reported.
1 finding from 1 review
Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
Mean number of oral ulcers · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
Depot corticosteroids (systemic; 40 mg methylprednisolone IM every 3… showed no clear difference in mean number of oral ulcers compared with placebo (saline IM injection); GRADE not reported.
1 finding from 1 review
Clinical resolution (oral lesion not completely resolved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
SoF 4, Clinical resolution (not completely resolved) at 3 to 6 months: '3 studies (freeze-dried black raspberry gel, green tea extract capsules, mixed tea) did not find evidence of benefit.' No GRADE. Effects text:…
4 studies
GRADE not reported
Malignant transformation (oral cancer development) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review