Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

374 questions · 377 findings · 63 reviews · Pregnancy and Childbirth

No studies found 88 · 23.3%GRADE not reported 32 · 8.5%Very low 92 · 24.4%Low 103 · 27.3%Moderate 50 · 13.3%High 12 · 3.2%

Oral misoprostol vs vaginal dinoprostone

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal dinoprostone (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal dinoprostone

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol probably leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal dinoprostone (moderate certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal misoprostol (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal misoprostol (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Admission to neonatal intensive care unit · women in the third trimester for induction of labour.

Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal misoprostol (moderate certainty).

1 finding from 1 review

Oral misoprostol vs intravenous (IV) oxytocin

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation with fetal heart rate changes compared with intravenous oxytocin (very low certainty).

1 finding from 1 review

Oral misoprostol vs intravenous (IV) oxytocin

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

It is very uncertain whether oral misoprostol changes uterine hyperstimulation without fetal heart rate changes compared with intravenous oxytocin (very low certainty).

1 finding from 1 review