Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,036 questions · 1,100 findings · 261 reviews

No studies found 160 · 14.5%GRADE not reported 188 · 17.1%Very low 270 · 24.5%Low 303 · 27.5%Moderate 139 · 12.6%High 40 · 3.6%

Hypnosis vs Conventional treatment

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether hypnosis changes self- or observational assessment of intraoperative… compared with conventional treatment (very low certainty).

1 finding from 1 review

Electrical counter-stimulation device (DentalVibe) vs Conventional treatment (no stimulation)

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether electrical counter-stimulation device (DentalVibe) changes self- or observational assessment of intraoperative… compared with conventional treatment (no stimulation) (very low certainty).

1 finding from 1 review

Audiovisual distraction vs Conventional treatment

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour during LA (negative vs positive behaviour; Frankl Behaviour Rating Scale) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether audiovisual distraction changes self- or observational assessment of intraoperative… compared with conventional treatment (very low certainty).

1 finding from 1 review

Camouflage syringe vs Conventional syringe

Self- or observational assessment of intraoperative distress/pain/acceptance of treatment during provision of LA: pain-related behaviour (crying) · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia

It is very uncertain whether camouflage syringe changes self- or observational assessment of intraoperative… compared with conventional syringe (very low certainty).

1 finding from 1 review

Pre-cooling of the injection site vs Conventional treatment

Intraoperative pain · Children and adolescents having dental treatment under local anaesthetic without general anaesthesia
1 finding from 1 review

Botulinum toxin type A vs placebo

Subjective participant assessment at 4 weeks; 755 participants(6 RCTs) · cervical dystonia

Botulinum toxin type A leads to higher subjective participant assessment at 4 weeks; 755 participants(6 RCTs) compared with placebo (high certainty).

1 finding from 1 review

'Driving whilst intoxicated' programme + incarceration vs incarceration alone

Reconviction (for drink‐driving) Assessed by: Cox regression of re‐arrest rates over 24 months Timing of assessment: 24 months · adults with antisocial personality disorder

It is very uncertain whether 'Driving whilst intoxicated' programme + incarceration changes reconviction (for drink‐driving) Assessed by: Cox regression of… compared with incarceration alone (very low certainty).

1 finding from 1 review

Schema therapy vs usual care

Adverse events Assessed by: number of participants with a global negative outcome (e.g. dropping out of therapy, recidivism or being transferred to another facility due to poor treatment response) overall Timing of assessment: over the 3 years · adults with antisocial personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial risk management ('Resettle' programme) vs usual care

Death during study period · adults with antisocial personality disorder

It is very uncertain whether psychosocial risk management ('Resettle' programme) changes adverse events: death during the study period Timing of assessment:… compared with treatment‐as‐usual (very low certainty).

1 finding from 1 review

Intervention not reported

Gait assessment · participants with relapsed or recurrent CTEV

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Gait assessment · participants with neglected CTEV

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Gait assessment · participants with CTEV (type of case (i.e. whether initial presentation or relapsed) not specified)

The review found no eligible studies for this question.

1 finding from 1 review