Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Misoprostol 800 µg plus mifepristone 200 mg vs mifepristone (200 mg) plus prostaglandin

Failure to achieve complete abortion · women undergoing first trimester abortion

Misoprostol 800 µg plus mifepristone 200 mg probably leads to lower failure to achieve complete abortion compared with misoprostol 400 µg plus mifepristone 200 mg (moderate certainty).

1 finding from 1 review

Misoprostol 800 µg plus mifepristone 200 mg vs mifepristone (200 mg) plus prostaglandin

Women's dissatisfaction with the procedure · women undergoing first trimester abortion

Misoprostol 800 µg plus mifepristone 200 mg probably leads to lower women's dissatisfaction with the procedure compared with misoprostol 400 µg plus mifepristone 200 mg (moderate certainty).

1 finding from 1 review

Oral vs vaginal administration of oestradiol and dydrogesterone

Uterine volume (cm³) · women with premature ovarian insufficiency (POI) awaiting oocyte donation
2 findings from 1 review

Low vs high 17ß‐oestradiol dose

Uterine volume (cm³) · young women with Turner syndrome who have completed pubertal induction
2 findings from 1 review

Active treatment vs observation

Eradication of MRSA · adults or children with positive microbiological isolate of MRSA from a respiratory tract specimen

Active treatment showed no clear difference in eradication of MRSA: number of participants that were MRSA‐negativea compared with observation only (low certainty).

1 finding from 1 review