Findings

What do systematic reviews say?

4,760 questions · 8,065 findings · 1,036 reviews

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No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Number of women with total blood loss 1000 mL or more after randomisation · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Mean blood loss (mL) (trialist defined) · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Blood transfusion (red cell or whole blood) · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intrauterine balloon tamponade (condom‐loaded catheter) vs uterovaginal packing (intrauterine tamponade versus another intrauterine tamponade method)

Side effects of the intervention (e.g. trauma, necrosis) ‐ fever · Women (aged between 20 and 40) diagnosed with primary PPH following 'normal' vaginal birth and unresponsive to medical treatment (Ashraf…

It is very uncertain whether intrauterine balloon tamponade (condom‐loaded catheter) changes side effects of the intervention (e.g. trauma, necrosis) ‐ fever compared with uterovaginal packing (intrauterine tamponade versus another… (very low certainty).

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
RR 0.47 [0.38, 0.59]
1 study · 212 participants
Very low

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

Mortality due to bleeding · women with uncontrolled atonic PPH following caesarean section, and not responding to standard care (uterine massage, ecbolics and…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

Hysterectomy to control bleeding · women with uncontrolled atonic PPH following caesarean section, and not responding to standard care (uterine massage, ecbolics and…

Modified B‐Lynch compression suture technique may leads to lower hysterectomy to control bleeding compared with standard B‐Lynch compression suture (one uterine compression suture… (low certainty).

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
RR 0.33 [0.11, 0.99]
1 study · 160 participants
Low

External uterine compression (all methods) plus normal care vs normal care

Blood transfusion (red cell or whole blood) · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

It is very uncertain whether external uterine compression (all methods) plus normal care changes blood transfusion (red cell or whole blood) compared with normal care (very low certainty).

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
RR 2.33 [0.66, 8.23]
1 study · 64 participants
Very low

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

Serious maternal morbidity (renal or respiratory failure, cardiac arrest or multiple organ failure) · women with uncontrolled atonic PPH following caesarean section, and not responding to standard care (uterine massage, ecbolics and…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

Number of women with total blood loss 1000 mL or more after randomisation · women with uncontrolled atonic PPH following caesarean section, and not responding to standard care (uterine massage, ecbolics and…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

Mean blood loss (mL) (trialist defined) · women with uncontrolled atonic PPH following caesarean section, and not responding to standard care (uterine massage, ecbolics and…

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

Blood transfusion (red cell or whole blood) · women with uncontrolled atonic PPH following caesarean section, and not responding to standard care (uterine massage, ecbolics and…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

Side effects of the intervention (e.g. trauma, necrosis) · women with uncontrolled atonic PPH following caesarean section, and not responding to standard care (uterine massage, ecbolics and…

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

External uterine compression (all methods) plus normal care vs normal care

Side effects of the intervention (e.g. trauma, necrosis) ‐ not reported · women diagnosed with primary PPH following vaginal birth. PPH was defined as quote: "blood loss > 500mL after delivery" p 601

The review found no eligible studies for this question.

1 finding from 1 review

Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes pain (mean score) compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
MD 0.62 [0.42, 0.82]
1 study · 42 participants
Very low

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical score compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
MD 0.56 [0.50, 0.62]
1 study · 42 participants
Very low

Clinical examination with 24-month recall vs Clinical examination with 12-month recall

Caries increment in permanent teeth · Regular-attending primary-care dental patients aged 3, 16 or 18 years at entry (aged up to 20; low caries risk)

It is very uncertain whether clinical examination with 24-month recall changes dental caries: DMFS increment (permanent teeth) compared with clinical examination with 12-month recall (very low certainty).

1 finding from 1 review

Recall intervals for oral health in primary care patients 2020 · Cochrane All outcomes
2 years · 16-20 year olds (permanent teeth)
MD 0.86 [-0.03, 1.75]
1 study · 127 participants
Very low

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical resolution compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Interventions for treating oral lichen planus: corticosteroid therapies 2020 · Cochrane All outcomes
RR 0.46 [0.22, 0.98]
1 study · 42 participants
Very low

Mechanical (high-volume) irrigation vs Manual (low-volume) irrigation

Presence of dry socket · Adults with mandibular third molars requiring removal

It is very uncertain whether mechanical (high-volume) irrigation changes alveolar osteitis compared with manual (low-volume) irrigation (very low certainty).

1 finding from 1 review

Surgical techniques for the removal of mandibular wisdom teeth 2020 · Cochrane All outcomes
1 week · mechanical vs manual
RR 0.33 [0.01, 8.09]
1 study · 99 participants
Very low

High-volume evacuation (HVE) vs Conventional dental suction (low-volume evacuator / saliva ejector)

Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling at 150 cm from mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting

It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with conventional dental suction (low-volume evacuator / saliva ejector) (very low certainty).

1 finding from 1 review

Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious diseases 2020 · Cochrane All outcomes
MD -2.20 [-14.01, 9.61]
1 study · 6 participants
Very low