Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,783 questions · 10,022 findings · 882 reviews

No studies found 2,100 · 21%GRADE not reported 1,013 · 10.1%Very low 2,237 · 22.3%Low 2,514 · 25.1%Moderate 1,709 · 17.1%High 449 · 4.5%

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Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes pain (mean score) compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical score compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Topical triamcinolone acetonide vs Photodynamic therapy

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether topical triamcinolone acetonide changes pain (mean score) compared with photodynamic therapy (very low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical resolution compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

BoNT‐A vs usual care or physiotherapy

Instrumented gait analysis (kinematics) (not measured) · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Function · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Range of motion (passive ankle dorsiflexion) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Satisfaction (not measured) · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Spasticity (ankle plantarflexors) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Adverse events · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Gait assessment ‐ not measured · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

Lithium vs ECT

Efficacy: response (categorical) YMRS change ≥ 50% from baseline to end of study · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Lithium vs ECT

Efficacy: response (continuous) MRS mean change from baseline to end of study · acute mania
1 finding from 1 review

Lithium vs ECT

Remission · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Lithium vs ECT

Acceptability: total withdrawals · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Lithium vs ECT

Adverse events · acute mania

The review found no eligible studies for this question.

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Amifostine vs no otoprotective intervention

Ototoxicity according to NCI CTC v2 criteria with intra‐arterial platinum (combined asymptomatic and symptomatic disease) Exact test method not reported · children with cancer treated with platinum‐based therapy

Amifostine showed no clear difference in ototoxicity according to NCICTCv2 criteria with intra‐arterial… compared with no otoprotective intervention (low certainty).

1 finding from 1 review