Adverse events(during · children or adults with Types I or II HAE
Lanadelumab showed no clear difference in adverse events(during compared with placebo or active control (low certainty).
1 finding from 1 review
Quality of lifeAngioedema Quality of Life scale (lower score is better)(during · children or adults with Types I or II HAE
1 finding from 1 review
Disability (any validated scale) (during · children or adults with Types I or II HAE
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events (during · children or adults with Types I or II HAE
Avoralstat showed no clear difference in adverse events (during compared with placebo (low certainty).
1 finding from 1 review
Risk of HAE attacks (during · children or adults with Types I or II HAE
Berotralstat showed no clear difference in risk of HAE attacks (during compared with placebo or active control (low certainty).
1 finding from 1 review
Change in number of HAE attacks (per week) · children or adults with Types I or II HAE
1 finding from 1 review
Intervention not reported
Total studies: 56 Total participants: 9419 · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
no estimate extracted
56 participants
GRADE not reported
Intervention not reported
Pins (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
It is very uncertain whether the intervention changes pins (No direct evidence, indirect evidence only) (very low certainty).
1 finding from 1 review
RR 1.03 [0.78, 1.37]
Studies not reported
Very low
Intervention not reported
Screws (3 RCTs; 152 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
It is very uncertain whether the intervention changes screws (3 RCTs; 152 participants)a (very low certainty).
1 finding from 1 review
Intervention not reported
Non‐operative treatment (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
It is very uncertain whether the intervention changes non‐operative treatment (No direct evidence, indirect evidence only) (very low certainty).
1 finding from 1 review
RR 1.1 [0.59, 2.07]
Studies not reported
Very low
Intervention not reported
Cemented modern unipolar hemiarthroplasty · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Total studies: 13 Total participants: 2744 · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
no estimate extracted
13 participants
GRADE not reported
Intervention not reported
Dynamic fixed angle plate (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Uncemented modern bipolar hemiarthroplasty (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intervention not reported
Cemented modern bipolar hemiarthroplasty (1 RCT; 120 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
Intervention not reported
Uncemented modern unipolar hemiarthroplasty (1 RCT; 201 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
Intervention not reported
Total hip arthroplasty (single articulation) (1 RCT; 120 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
Intervention not reported
Dynamic fixed angle plate (2 RCTs; 246 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
It is very uncertain whether the intervention changes dynamic fixed angle plate (2 RCTs; 246 participants)a (very low certainty).
1 finding from 1 review
Intervention not reported
Screws (1 RCT; 60 participants)a · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
Intervention not reported
Non‐operative treatment (No direct evidence, indirect evidence only) · older adults (> 60 years of age) with intracapsular hip fractures; most fractures in the included studies were displaced
1 finding from 1 review
no estimate extracted
Studies not reported
Very low