Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Intervention not reported

MMRV randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMRV randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMR+V randomised controlled trial ‐ any severity ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMR+V randomised controlled trial ‐ any severity ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMR+V randomised controlled trial ‐ any severity ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMR+V randomised controlled trial ‐ any severity ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMR+V randomised controlled trial ‐ any severity ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMR+V randomised controlled trial ‐ any severity ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMR+V randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMR+V randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMR+V randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMR+V randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMR+V randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMR+V randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

Temperature ‐ RCT/CCT axillary · children 9 months to 15 years old

The intervention may leads to higher temperature ‐ RCT/CCT axillary (low certainty).

1 finding from 1 review

Intervention not reported

Temperature ‐ RCT/CCT rectal · children 9 months to 15 years old

The intervention showed no clear difference in temperature ‐ RCT/CCT rectal (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies household contacts ‐ 1 dose · children 9 months to 15 years old

The intervention may leads to lower cohort studies household contacts ‐ 1 dose (low certainty).

1 finding from 1 review

Intervention not reported

Temperature ‐ RCT/CCT measurement site not reported · children 9 months to 15 years old

The intervention showed no clear difference in temperature ‐ RCT/CCT measurement site not reported (high certainty).

1 finding from 1 review

Intervention not reported

Temperature ‐ cohort studies orally · children 9 months to 15 years old

It is very uncertain whether the intervention changes temperature ‐ cohort studies orally (very low certainty).

1 finding from 1 review

Intervention not reported

Temperature ‐ cohort studies measurement site not reported · children 9 months to 15 years old

It is very uncertain whether the intervention changes temperature ‐ cohort studies measurement site not reported (very low certainty).

1 finding from 1 review

Intervention not reported

Rash ‐ cohort studies · children 9 months to 15 years old

It is very uncertain whether the intervention changes rash ‐ cohort studies (very low certainty).

1 finding from 1 review

Intervention not reported

Lymphadenopathy ‐ RCT/CCT · children 9 months to 15 years old

The intervention showed no clear difference in lymphadenopathy ‐ RCT/CCT (moderate certainty).

1 finding from 1 review

Intervention not reported

Lymphadenopathy ‐ cohort studies · children 9 months to 15 years old

It is very uncertain whether the intervention changes lymphadenopathy ‐ cohort studies (very low certainty).

1 finding from 1 review

Intervention not reported

Coryza ‐ RCT/CCT · children 9 months to 15 years old

The intervention showed no clear difference in coryza ‐ RCT/CCT (moderate certainty).

1 finding from 1 review

Intervention not reported

Coryza ‐ cohort studies · children 9 months to 15 years old

The intervention may leads to higher coryza ‐ cohort studies (low certainty).

1 finding from 1 review

Intervention not reported

URTI (rhinitis pharyngitis) ‐ RCT/CCT · children 9 months to 15 years old

The intervention showed no clear difference in URTI (rhinitis pharyngitis) ‐ RCT/CCT (low certainty).

1 finding from 1 review

Intervention not reported

URTI (rhinitis pharyngitis) ‐ cohort studies · children 9 months to 15 years old

It is very uncertain whether the intervention changes URTI (rhinitis pharyngitis) ‐ cohort studies (very low certainty).

1 finding from 1 review