Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,092 questions · 3,199 findings · 339 reviews · Headline outcomes only

No studies found 714 · 22.3%GRADE not reported 181 · 5.7%Very low 695 · 21.7%Low 908 · 28.4%Moderate 568 · 17.8%High 133 · 4.2%

Boswellia serrata vs valdecoxib

Adverse events Participants (n) reported adverse events · patients with treating osteoarthritis

It is very uncertain whether boswellia serrata changes adverse events Participants (n) reported adverse events compared with valdecoxib (very low certainty).

1 finding from 1 review

Boswellia serrata vs valdecoxib

Withdrawals due to adverse events · patients with treating osteoarthritis

It is very uncertain whether boswellia serrata changes adverse events Participants (n) withdrew due to adverse effects compared with valdecoxib (very low certainty).

1 finding from 1 review

Intervention not reported

Pain Global pain VAS 0‐100 (higher scores mean worse) · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Function Multiple tools4 · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported adverse events · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) withdrew due to adverse effects (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with treating osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported serious adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Radiographic joint changes Change in Joint Space Width (JSW) from baseline (higher scores mean worse). · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Quality of life · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pain Global pain VAS 0‐100 (higher scores mean worse) · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Function Lequesne algofunctional index 0‐24 (higher scores mean worse) · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported adverse events · patients with osteoarthritis

The intervention showed no clear difference in adverse events Participants (n) reported adverse events (moderate certainty).

1 finding from 1 review

Intervention not reported

Adverse events Participants (n) withdrew due to adverse effects · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Adverse events Participants (n) reported serious adverse events · patients with osteoarthritis
1 finding from 1 review

Intervention not reported

Radiographic joint changes · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of life · patients with osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review