Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Probiotics vs antibiotic prophylaxis

Renal parenchymal defects on DMSA scan ‐ Patient data at 1 year · primary VUR

Probiotics showed no clear difference in renal parenchymal defects on DMSA scan ‐ Patient data at 1 year compared with antibiotic prophylaxis (low certainty).

1 finding from 1 review

Surgical reimplantation of ureters plus antibiotics vs antibiotics alone

Febrile UTI by 5 years: surgical correction + antibiotics versus antibiotics alone · primary VUR

Surgical reimplantation of ureters plus antibiotics probably leads to lower febrile UTI by 5 years: surgical correction + antibiotics versus… compared with antibiotics alone (moderate certainty).

1 finding from 1 review

Intervention not reported

Microfilaraemia (mf) prevalence · people with lymphatic filariasis or communities where lymphatic filariasis is endemic

The intervention showed no clear difference in microfilaraemia (mf) prevalence (high certainty).

1 finding from 1 review