Search

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

407 questions · 418 findings · 14 reviews · Endodontics and dental trauma

No studies found 104 · 24.9%GRADE not reported 201 · 48.1%Very low 61 · 14.6%Low 41 · 9.8%Moderate 11 · 2.6%High 0 · 0%

Non-rinse conditioner + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether non-rinse conditioner + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review

Intermediate restorative material (IRM) root-end filling vs SuperEBA

Healing - 1 year or longer · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether intermediate restorative material (IRM) root-end filling changes healing - 1 year or longer compared with superEBA (very low certainty).

1 finding from 1 review

Papilla base incision (PBI) vs Complete papilla mobilisation (sulcular incision)

Postoperative pain (VAS 0-100) - 3 days · People requiring retreatment of periapical lesions (failed root canal therapy)

Papilla base incision (PBI) led to lower postoperative pain (VAS 0-100) - 3 days compared with complete papilla mobilisation (sulcular incision); GRADE not reported.

1 finding from 1 review

Platelet-rich fibrin (PRF) graft vs No grafting

Radiographic healing - 1 year · People requiring retreatment of periapical lesions (failed root canal therapy)
1 finding from 1 review
  • Angerame 2015 (7 test, 4 control): no significant difference in healing of the lesion at 1 year; significant difference only at 2- and 3-month follow-up. Small preliminary study; no robust pooled analysis.
    1 study · 11 participants
    GRADE not reported

Cone beam computed tomography (CBCT) preoperative evaluation vs Conventional periapical radiography

Healing - 1 year · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether cone beam computed tomography (CBCT) preoperative evaluation changes healing - 1 year compared with conventional periapical radiography (very low certainty).

1 finding from 1 review

Mineral trioxide aggregate (MTA) root-end filling vs Intermediate restorative material (IRM)

Prevalence of pain - 1 day · People requiring retreatment of periapical lesions (failed root canal therapy)

Mineral trioxide aggregate (MTA) root-end filling showed no clear difference in prevalence of pain - 1 day compared with intermediate restorative material (IRM) (low certainty).

1 finding from 1 review

Papilla base incision (PBI) vs Complete papilla mobilisation (sulcular incision)

Postoperative pain (VAS 0-100) - 2 days · People requiring retreatment of periapical lesions (failed root canal therapy)

Papilla base incision (PBI) showed no clear difference in postoperative pain (VAS 0-100) - 2 days compared with complete papilla mobilisation (sulcular incision); GRADE not reported.

1 finding from 1 review

Papilla base incision (PBI) vs Complete papilla mobilisation (sulcular incision)

Postoperative pain (VAS 0-100) - 1 day · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether papilla base incision (PBI) changes postoperative pain (VAS 0-100) - 1 day compared with complete papilla mobilisation (sulcular incision) (very low certainty).

1 finding from 1 review

Preoperative antibiotics vs placebo

Occurrence of postoperative infection - 4 weeks · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether preoperative antibiotic prophylaxis changes occurrence of postoperative infection - 4 weeks compared with placebo (very low certainty).

1 finding from 1 review

Mineral trioxide aggregate (MTA) root-end filling vs Intermediate restorative material (IRM)

Healing rate · People requiring retreatment of periapical lesions (failed root canal therapy)

Mineral trioxide aggregate (MTA) root-end filling showed no clear difference in healing - 2 years compared with intermediate restorative material (IRM); GRADE not reported.

1 finding from 1 review

Root-end resection (with or without root-end filling; surgical retreatment) vs Non-surgical re-treatment (orthograde root canal therapy)

Healing rate · People with one or more endodontically treated teeth and a periapical condition requiring retreatment

Root-end resection (with or without root-end filling; surgical… showed no clear difference in healing - 10 years compared with root canal retreatment (non-surgical/orthograde); GRADE not reported.

2 findings from 1 review

Papilla base incision (PBI) vs Complete papilla mobilisation (sulcular incision)

Height loss of interdental papilla - 1 year · People requiring retreatment of periapical lesions (failed root canal therapy)

It is very uncertain whether papilla base incision (PBI) changes height loss of interdental papilla - 1 year compared with complete papilla mobilisation (sulcular incision) (very low certainty).

1 finding from 1 review