Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

338 questions · 369 findings · 33 reviews

No studies found 91 · 24.7%GRADE not reported 68 · 18.4%Very low 125 · 33.9%Low 49 · 13.3%Moderate 32 · 8.7%High 4 · 1.1%

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Frequency of joint noise · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes frequency of joint noise compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Muscle pain at rest · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes muscle pain at rest compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Somatisation · People with temporomandibular disorders (TMD)

Occlusal splint showed no clear difference in somatisation compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Range of mandibular motion · People with temporomandibular disorders (TMD)

Occlusal splint showed no clear difference in range of mandibular motion compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes pain (mean score) compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical score compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical resolution compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Subthreshold vs standard macular photocoagulation

Anatomic measures: partial to complete resolution of the macular oedema with stereoscopic fundus photography or biomicroscopy; leakage on fluorescein angiography (IVFA); and, if available, retinal macular thickness with OCT · people with diabetic macular oedema

Subthreshold showed no clear difference in anatomic measures: partial to complete resolution of the macular… compared with standard macular photocoagulation (low certainty).

1 finding from 1 review

Subthreshold vs standard macular photocoagulation

Improvement of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS lines or 0.3 logMAR · people with diabetic macular oedema

It is very uncertain whether subthreshold changes improvement of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS… compared with standard macular photocoagulation (very low certainty).

1 finding from 1 review

Subthreshold vs standard macular photocoagulation

Worsening of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS lines or 0.3 logMAR · people with diabetic macular oedema

It is very uncertain whether subthreshold changes worsening of BCVA defined as ≥ 15 ETDRS letters (i.e. 3 ETDRS lines… compared with standard macular photocoagulation (very low certainty).

1 finding from 1 review