Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,734 questions · 15,288 findings · 893 reviews

No studies found 3,864 · 25.3%GRADE not reported 2,222 · 14.5%Very low 3,868 · 25.3%Low 3,280 · 21.5%Moderate 1,676 · 11%High 378 · 2.5%

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Locking plate vs locking intramedullary nail

Adverse events: number of participants with complications · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)

It is very uncertain whether locking plate changes adverse events: number of participants with complications compared with locking intramedullary nail (very low certainty).

1 finding from 1 review

Reverse total shoulder arthroplasty (RTSA) vs hemiarthroplasty

Self‐reported shoulder function · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)
3 findings from 1 review

Reverse total shoulder arthroplasty (RTSA) vs hemiarthroplasty

Adverse events: number of participants with complications · adults undergoing surgery for displaced proximal humeral fracturesa (2 trials)

It is very uncertain whether reverse total shoulder arthroplasty (RTSA) changes adverse events: number of participants with complications compared with hemiarthroplasty (very low certainty).

1 finding from 1 review

Calcineurin inhibitors ± oral steroids vs oral steroids alone

Complete remission · minimal change disease in adults with nephrotic syndrome

Calcineurin inhibitors ± oral steroids showed no clear difference in complete remission Time frame: 2 to 6 months compared with oral steroids alone (moderate certainty).

1 finding from 1 review

Calcineurin inhibitors ± oral steroids vs oral steroids alone

Complete or partial remission · minimal change disease in adults with nephrotic syndrome

Calcineurin inhibitors ± oral steroids showed no clear difference in complete or partial remission time frame: 3 to 6 months compared with oral steroids alone (moderate certainty).

1 finding from 1 review