Hospital mortality · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in hospital mortality compared with usual care (low certainty).
1 finding from 1 review
Duration of ICU stay · mechanically ventilated ICU adults and children requiring sedation management
1 finding from 1 review
Length of hospital stay · mechanically ventilated ICU adults and children requiring sedation management
1 finding from 1 review
Adverse event ‐ incidence of self‐extubation (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in adverse event ‐ incidence of self‐extubation (in ICU) compared with usual care (high certainty).
1 finding from 1 review
Adverse event ‐ incidence of reintubation (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in adverse event ‐ incidence of reintubation (in ICU) compared with usual care (low certainty).
1 finding from 1 review
Incidence of tracheostomy (in ICU) · mechanically ventilated ICU adults and children requiring sedation management
Protocol‐directed sedation management showed no clear difference in incidence of tracheostomy (in ICU) compared with usual care (low certainty).
1 finding from 1 review
Number of delirium ‐ and coma‐free days (within 28 days) measured by CAM‐ICU or ICDSC · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Ventilator‐free days (within the first 30 days) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Duration of ICU stay · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
It is very uncertain whether physical and cognitive therapy changes length of ICU stay (days) compared with standard care (very low certainty).
1 finding from 1 review
Cognitive function · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Cognitive functioning b) Executve functioning (DEX score) (scores range from 0 to 80. Lower scores indicate better functioning) (DEX) · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
Adverse events · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
1 finding from 1 review
In‐hospital mortality within 28 days. · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…
Haloperidol showed no clear difference in in‐hospital mortality within 28 days. compared with placebo (moderate certainty).
1 finding from 1 review
Number of delirium ‐ and coma‐free days (within 28 days) measured by CAM‐ICU or ICDSC · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…
1 finding from 1 review
Ventilator‐free days up to day 28 · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…
1 finding from 1 review
Duration of ICU stay · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…
1 finding from 1 review
Cognitive impairment · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…
1 finding from 1 review
The event rate of ICU delirium measured by the CAM‐ICU · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
In‐hospital mortality at 30 days or at the longest · critically ill patients 18 years or older treated for respiratory failure or septic or both, cardiogenic or haemorrhagic shock who resided…
It is very uncertain whether physical and cognitive therapy changes in‐hospital mortality at 30 days or at the longest compared with standard care (very low certainty).
1 finding from 1 review