Findings

What do systematic reviews say?

4,410 questions · 8,901 findings · 1,091 reviews

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No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

High‐dose vs low‐dose regimens of thrombolytic agents

30‐Day amputation‐free survival · patients with < 42 days' limb ischaemiaa

1 finding from 1 review

Infusion techniques for peripheral arterial thrombolysis 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 302 participants
Very low

High‐dose vs low‐dose regimens of thrombolytic agents

Amputation · patients with < 42 days' limb ischaemiaa

1 finding from 1 review

Infusion techniques for peripheral arterial thrombolysis 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 302 participants
Very low

Topical ointment or cream vs routine skin care

Invasive infection (before hospital discharge) · preterm infants with low birth weight

Topical ointment or cream showed no clear difference in invasive infection until hospital discharge compared with routine skin care (low certainty).

1 finding from 1 review

Topical emollient for preventing infection in preterm infants 2021 · Cochrane Headline outcomes only
RR 1.13 [0.97, 1.31]
8 studies · 2086 participants
Low

Topical ointment or cream vs routine skin care

Mortality before hospital discharge · preterm infants with low birth weight

Topical ointment or cream showed no clear difference in mortality until hospital discharge (or latest reported) compared with routine skin care (low certainty).

1 finding from 1 review

Topical emollient for preventing infection in preterm infants 2021 · Cochrane Headline outcomes only
RR 0.87 [0.75, 1.03]
7 studies · 2067 participants
Low

Topical oil vs routine skin care

Invasive infection (any organism) · preterm infants with low birth weight

Topical oil may leads to lower invasive infectionuntil hospital discharge compared with routine skin care (low certainty).

1 finding from 1 review

Topical emollient for preventing infection in preterm infants 2021 · Cochrane Headline outcomes only
RR 0.71 [0.52, 0.96]
9 studies · 3256 participants
Low

Topical oil vs routine skin care

Mortality before hospital discharge · preterm infants with low birth weight

Topical oil showed no clear difference in mortality until hospital discharge (or latest reported) compared with routine skin care (low certainty).

1 finding from 1 review

Topical emollient for preventing infection in preterm infants 2021 · Cochrane Headline outcomes only
RR 0.94 [0.82, 1.08]
11 studies · 1119 participants
Low

Topical ointment or cream vs oil

Invasive infection (any organism) · preterm infants with low birth weight

Topical ointment or cream showed no clear difference in invasive infectionuntil hospital discharge compared with oil (low certainty).

1 finding from 1 review

Topical emollient for preventing infection in preterm infants 2021 · Cochrane Headline outcomes only
RR 0.91 [0.57, 1.46]
1 study · 316 participants
Low

Topical ointment or cream vs oil

Mortality before hospital discharge · preterm infants with low birth weight

Topical ointment or cream may leads to lower mortality until hospital discharge (or latest reported) compared with oil (low certainty).

1 finding from 1 review

Topical emollient for preventing infection in preterm infants 2021 · Cochrane Headline outcomes only
RR 0.82 [0.68, 0.98]
1 study · 316 participants
Low

Topical oil vs another oil

Invasive infection (any organism) · preterm infants with low birth weight

1 finding from 1 review

Topical emollient for preventing infection in preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 64 participants
Very low

Topical oil vs another oil

Mortality before hospital discharge · preterm infants with low birth weight

1 finding from 1 review

Topical emollient for preventing infection in preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 64 participants
Very low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

Change in arterial partial pressure of oxygen · post‐exacerbation COPD

2 findings from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 234 participants
Low
Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 170 participants
Low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

Change in arterial partial pressure of carbon dioxide · post‐exacerbation COPD

2 findings from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 241 participants
Moderate
Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 175 participants
High

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

Change in the health‐related quality of life · post‐exacerbation COPD

2 findings from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 219 participants
Very low
Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 164 participants
Very low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

Admission‐free survival · post‐exacerbation COPD

Summary of Findings Table ‐ Chronic non‐invasive ventilation may leads to lower admission‐free survival compared with standard treatment following a severe exacerbation (low certainty).

1 finding from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
HR 0.71 [0.54, 0.94]
2 studies · 317 participants
Low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

All‐cause mortality · post‐exacerbation COPD

Summary of Findings Table ‐ Chronic non‐invasive ventilation showed no clear difference in all‐cause mortality compared with standard treatment following a severe exacerbation (low certainty).

1 finding from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
HR 0.97 [0.74, 1.28]
2 studies · 318 participants
Low

Intermittent rectal diclofenac vs placebo followed after 8 hours by oral ibuprofen, acetaminophen or placebo

Recurrent seizure at 6 months · children with febrile seizures

Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 6 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
RR 0.8 [0.42, 1.55]
1 study · 231 participants
High

Intermittent rectal diclofenac vs placebo followed after 8 hours by oral ibuprofen, acetaminophen or placebo

Recurrent seizure at 12 months · children with febrile seizures

Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 12 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
RR 0.69 [0.4, 1.16]
1 study · 231 participants
High

Intermittent rectal diclofenac vs placebo followed after 8 hours by oral ibuprofen, acetaminophen or placebo

Recurrent seizure at 18 months · children with febrile seizures

Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 18 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
RR 0.72 [0.45, 1.16]
1 study · 231 participants
High

Intermittent rectal diclofenac vs placebo followed after 8 hours by oral ibuprofen, acetaminophen or placebo

Recurrent seizure at 24 months · children with febrile seizures

Intermittent rectal diclofenac showed no clear difference in recurrent seizure at 24 months compared with placebo, followed by oral ibuprofen, paracetamol, or placebo after 8… (high certainty).

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
RR 0.79 [0.51, 1.24]
1 study · 231 participants
High

Intermittent rectal diclofenac vs placebo followed after 8 hours by oral ibuprofen, acetaminophen or placebo

Recurrent seizure at 36 months · children with febrile seizures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic drug management for febrile seizures in children 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found