Findings

What do systematic reviews say?

4,720 questions · 15,377 findings · 900 reviews

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No studies found 3,865 · 25.1%GRADE not reported 2,291 · 14.9%Very low 3,875 · 25.2%Low 3,287 · 21.4%Moderate 1,681 · 10.9%High 378 · 2.5%

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Vestibular rehabilitation vs placebo or no treatment

Improvement in vertigo · adults with PPPD

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for persistent postural‐perceptual dizziness (PPPD) 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Vestibular rehabilitation vs placebo or no treatment

Change in vertigo · adults with PPPD

The review found no eligible studies for this question.

1 finding from 1 review

Non‐pharmacological interventions for persistent postural‐perceptual dizziness (PPPD) 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical anesthetics vs placebo or no intervention

Successful LP on first attempt № of LPs: 100(1 quasi‐RCT) · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical anesthetics vs placebo or no intervention

Total number of LP attempts № of LPs: 100(1 quasi‐RCT) · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical anesthetics vs placebo or no intervention

Episodes of bradycardia · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical anesthetics vs placebo or no intervention

NFCS pain score during the procedure№ of infants: 112(2 RCTs) Score · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Topical anesthetics vs placebo or no intervention

Episodes of desaturation, defined as a decrease of SpO2 to less than 80%, with no minimum duration specified—not reported · lumbar puncture in newborn infants

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Topical anesthetics vs placebo or no intervention

Apnea: number of episodesduring the procedure · lumbar puncture in newborn infants

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical anesthetics vs placebo or no intervention

Episodes of apnea · lumbar puncture in newborn infants

It is very uncertain whether topical anesthetics changes apnea: occurrence of one or more episodes№ of LPs: 100(1 quasi‐RCT) compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions for the management of pain and discomfort during lumbar puncture in newborn infants 2023 · Cochrane Headline outcomes only
RR 3.24 [0.14, 77.79]
Studies not reported
Very low

Superselective neck dissection vs Elective selective neck dissection

Adverse events associated with treatment · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Adverse events: no adverse events reported; 72 participants (2 RCTs).
2 studies · 72 participants
Very low

Superselective neck dissection vs Elective selective neck dissection

Total mortality · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Total mortality: not reported.
0 studies
No studies found

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Total number of orthodontic appliance adjustment appointments during treatment · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
Total number of orthodontic appliance adjustment appointments required during treatment stage | Not reported
Studies not reported
No studies found

Supraomohyoid neck dissection vs Modified radical neck dissection

Disease-free survival · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Disease-free survival: not reported (Guo 2014 reported disease-specific survival, not a review outcome).
0 studies
No studies found

Sentinel node biopsy (neck dissection only if biopsy positive) vs Elective neck dissection

Total mortality · Adults with oral cavity or oropharyngeal cancer

Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in total mortality compared with elective neck dissection (low certainty).

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
3 years
HR 1.00 [0.90, 1.11]
1 study · 279 participants
Low

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Recurrence · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
oral cavity
Recurrence: not reported for the oral cancer subgroup (Iyer 2015).
0 studies
No studies found

Surgery vs Radiotherapy alone

Disease-free survival · Adults with oropharyngeal cancer

Surgery showed no clear difference in disease-free survival (new disease, progression, and mortality) compared with radiotherapy alone (low certainty).

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
3 years
HR 1.07 [0.27, 4.22]
1 study · 68 participants
Low

Surgery vs Radiotherapy alone

Recurrence · Adults with oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Recurrence: not reported.
0 studies
No studies found

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Rate of orthodontic tooth movement with removable orthodontic aligners · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

Light vibrational forces (LVF) showed no clear difference in rate of orthodontic tooth movement with removable orthodontic aligners compared with conventional orthodontic appliance treatment (placebo or no adjunct); GRADE not reported.

1 finding from 1 review

Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
Full aligner treatment duration
MD 0.2 [-1.51, 1.10]
1 study · 27 participants
GRADE not reported

Light-emitting diode (LED) photobiomodulation vs Conventional orthodontic appliance treatment

Rate of orthodontic tooth movement during space closure stage (maxillary canine distalisation), mm/day · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

It is very uncertain whether light-emitting diode (LED) photobiomodulation changes rate of orthodontic tooth movement during space closure stage… compared with conventional orthodontic appliance treatment (very low certainty).

1 finding from 1 review

Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
Space closure (canine retraction)
MD 0.006 [0, 0.02]
1 study · 39 participants
Very low

Low‐level laser therapy vs Conventional orthodontic appliance treatment

Orthodontically-induced inflammatory root resorption (OIIRR) during molar intrusion · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment

1 finding from 1 review

Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
Abellan 2021 assessed OIIRR using CBCT after intrusion of maxillary molars; no evidence of significant increase or reduction with LLLT. Statistical test results not published.
1 study
GRADE not reported