Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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Vitapex (calcium hydroxide/iodoform) vs 3Mix (ciprofloxacin + metronidazole + minocycline)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with 3Mix (ciprofloxacin + metronidazole + minocycline); GRADE not reported.

1 finding from 1 review

Cysteamine vs methionine (randomised trials)

Hepatotoxicity (aspartate aminotransferase > 1000 IU/L) · people with paracetamol (acetaminophen) overdose

It is very uncertain whether cysteamine changes hepatotoxicity (aspartate aminotransferase > 1000 U/L) compared with methionine (randomised trials) (very low certainty).

1 finding from 1 review

Honey vs dextromethorphan

Somnolence · acute cough in children

Honey showed no clear difference in drowsiness compared with dextromethorphan (low certainty).

1 finding from 1 review

Honey vs dextromethorphan

Nervousness, insomnia, hyperactivity · acute cough in children

Honey showed no clear difference in nervousness, insomnia, hyperactivity compared with dextromethorphan (low certainty).

1 finding from 1 review

Honey vs dextromethorphan

Stomachache, nausea, and vomiting · acute cough in children

Honey showed no clear difference in stomachache, nausea, and vomiting compared with dextromethorphan (low certainty).

1 finding from 1 review

Operative hysteroscopy vs control

Clinical pregnancya Ultrasound 4 intrauterine insemination cycles · subfertile women with endometrial polyps diagnosed by ultrasonography prior to treatment with gonadotropin and intrauterine insemination

Operative hysteroscopy may leads to higher clinical pregnancya Ultrasound 4 intrauterine insemination cycles compared with control (low certainty).

1 finding from 1 review