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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

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No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Doubling serum creatinine · proteinuric chronic kidney disease

Non‐steroidal mineralocorticoid receptor antagonist showed no clear difference in doubling serum creatinine compared with selective aldosterone antagonist (low certainty).

1 finding from 1 review

Intervention not reported

Overall mortality · alcohol consumers with high blood pressure

The intervention showed no clear difference in overall mortality (low certainty).

1 finding from 1 review

Intervention not reported

Cardiovascular events · alcohol consumers with high blood pressure

It is very uncertain whether the intervention changes cardiovascular events (very low certainty).

1 finding from 1 review

Intervention not reported

Decrease in systolic blood pressure (mmHg) · alcohol consumers with high blood pressure
1 finding from 1 review

Intervention not reported

Decrease in diastolic blood pressure (mmHg) · alcohol consumers with high blood pressure
1 finding from 1 review

Intervention not reported

Decrease in alcohol intake (g) · alcohol consumers with high blood pressure
1 finding from 1 review

Intervention not reported

Proportion of subjects with SBP < 140 mmHg and DBP < 90 mmHg · alcohol consumers with high blood pressure

It is very uncertain whether the intervention changes proportion of subjects with SBP < 140 mmHg and DBP < 90 mmHg (very low certainty).

1 finding from 1 review

Supine midline head position vs any other supine head position

Intraventricular haemorrhage · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes intraventricular haemorrhage, any grade compared with any other supine head position (very low certainty).

1 finding from 1 review

Supine midline head position vs any other supine head position

Intraventricular haemorrhage, Papile grade 3/4 · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes intraventricular haemorrhage, grade 3 to 4 compared with any other supine head position (very low certainty).

1 finding from 1 review

Supine midline head position vs any other supine head position

All‐cause mortality during hospital stay · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes mortality during initial hospitalisation compared with any other supine head position (very low certainty).

1 finding from 1 review

Supine midline head position vs any other supine head position

Retinopathy of prematurity, > stage 3 · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes retinopathy of prematurity, > stage 3 compared with any other supine head position (very low certainty).

1 finding from 1 review