Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

358 questions · 403 findings · 68 reviews

No studies found 43 · 10.7%GRADE not reported 121 · 30%Very low 128 · 31.8%Low 66 · 16.4%Moderate 33 · 8.2%High 12 · 3%

5% CP gel in tray (with STPP) vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 5% CP gel in tray (with STPP) changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review

10% CP gel in tray vs 10% CP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 10% CP gel in tray (Opalescence) changes tooth whitening - assessed by the dentist compared with 10% CP gel in tray (NiteWhite Excel) (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs human milk feeding ‐ low‐risk infants

All allergic disease ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes all allergic disease ‐ childhood (incidence) compared with human milk feeding ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs cow's milk formula

Food allergy ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes food allergy ‐ childhood (incidence) compared with cow's milk formula ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs cow's milk formula

Cow's milk allergy ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes cow's milk allergy ‐ childhood (incidence) compared with cow's milk formula ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs human milk feeding ‐ low‐risk infants

Asthma ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes asthma ‐ childhood (incidence) compared with human milk feeding ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs human milk feeding ‐ low‐risk infants

Eczema ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes eczema ‐ childhood (incidence) compared with human milk feeding ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs human milk feeding ‐ low‐risk infants

Food allergy ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes food allergy ‐ childhood (incidence) compared with human milk feeding ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs human milk feeding ‐ low‐risk infants

Cow's milk allergy ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes cow's milk allergy ‐ childhood (incidence) compared with human milk feeding ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs cow's milk formula

All allergic disease ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes all allergic disease ‐ childhood (incidence) compared with cow's milk formula ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs cow's milk formula

Asthma ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes asthma ‐ childhood (incidence) compared with cow's milk formula ‐ low‐risk infants (very low certainty).

1 finding from 1 review

Early short‐term feeding: hydrolysed formula vs cow's milk formula

Eczema ‐ childhood (incidence) · infants not selected for allergic disease risk.

It is very uncertain whether early short‐term feeding: hydrolysed formula changes eczema ‐ childhood (incidence) compared with cow's milk formula ‐ low‐risk infants (very low certainty).

1 finding from 1 review

10% CP gel in tray vs 7.5% HP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 10% CP gel in tray changes tooth whitening - assessed by the dentist compared with 7.5% HP gel in tray (very low certainty).

1 finding from 1 review

10% CP gel in tray vs 6% HP gel in tray

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 10% CP gel in tray changes tooth whitening - assessed by the dentist compared with 6% HP gel in tray (very low certainty).

2 findings from 1 review

17% CP gel in tray vs 10% CP gel in tray

Tooth whitening - reported by the patient · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 17% CP gel in tray changes tooth whitening - reported by the patient compared with 10% CP gel in tray (very low certainty).

1 finding from 1 review

5.9% HP strip vs 5.9% HP paint-on gel

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

5.9% HP strip led to higher tooth whitening - assessed by the dentist compared with 5.9% HP paint-on gel; GRADE not reported.

2 findings from 1 review