Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

303 questions · 321 findings · 26 reviews · Gynaecology and Fertility

No studies found 64 · 19.9%GRADE not reported 3 · 0.9%Very low 67 · 20.9%Low 104 · 32.4%Moderate 77 · 24%High 6 · 1.9%

Biological graft vs native tissue repair

Awareness of prolapse (subjective failure) (16‐24 months) · women with posterior vaginal wall prolapse

Biological graft showed no clear difference in awareness of prolapse (subjective failure) (16‐24 months) compared with native tissue repair (moderate certainty).

1 finding from 1 review

Biological graft vs native tissue repair

Recurrent posterior vaginal wall prolapse (objective failure) (12‐25 months) · women with posterior vaginal wall prolapse

Biological graft showed no clear difference in recurrent posterior vaginal wall prolapse (objective failure) (16‐24… compared with native tissue repair (low certainty).

1 finding from 1 review

Biological graft vs native tissue repair

Postoperative obstructed defecation (16‐24 months) · women with posterior vaginal wall prolapse

Biological graft showed no clear difference in postoperative obstructed defecation (16‐24 months) compared with native tissue repair (moderate certainty).

1 finding from 1 review

Biological graft vs native tissue repair

Postoperative complications (including wound infection) (16‐24 months) · women with posterior vaginal wall prolapse

Biological graft probably leads to higher postoperative complications (including wound infection) (16‐24 months) compared with native tissue repair (moderate certainty).

1 finding from 1 review

Transanal repair vs transvaginal repair

Recurrent posterior vaginal wall prolapse (objective failure) (12‐25 months) · women with posterior vaginal wall prolapse

Transanal repair probably leads to higher recurrent posterior vaginal wall prolapse (objective failure) (12‐25… compared with transvaginal repair (moderate certainty).

1 finding from 1 review