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Evidence found and GRADE certainty

322 questions · 356 findings · 39 reviews

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No studies found 67 · 18.8%GRADE not reported 15 · 4.2%Very low 107 · 30.1%Low 122 · 34.3%Moderate 44 · 12.4%High 1 · 0.3%

Transference‐Focused Psychotherapy (TFP) vs community treatment by experts (CTBE)

Suicidality ‐ CBT vs. TAUno. of participants with suicidal act (last 12 months) · patients with borderline personality disorder

Transference‐Focused Psychotherapy (TFP) showed no clear difference in suicidalityno. of participants with suicidal act (last 12 months) compared with community treatment by experts (CTBE) (moderate certainty).

1 finding from 1 review

Transference‐Focused Psychotherapy (TFP) vs community treatment by experts (CTBE)

Parasuicidality ‐ CBT vs. TAUno. of participants with self‐harming behaviour (last 12 months) · patients with borderline personality disorder

Transference‐Focused Psychotherapy (TFP) showed no clear difference in parasuicidalityno. of participants with self‐harming behaviour (last… compared with community treatment by experts (CTBE) (moderate certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care showed no clear difference in self‐reported depressive symptoms short term (up to 6 months) ‐ BDI… compared with usual care alone (moderate certainty).

8 findings from 1 review
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Psychotherapy as an adjunct to usual care vs usual care

Dropout · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care showed no clear difference in dropout medium term (7 to 12 months)* compared with usual care alone (moderate certainty).

2 findings from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Response (50% reduction in BDI) medium term (7 to 12 months)* · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) medium term (7 to 12 months)* compared with usual care alone (low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Response (50% reduction in BDI) long term (longer than 12 months)* · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in BDI) long term (longer than 12 months)* compared with usual care alone (low certainty).

1 finding from 1 review

Psychotherapy as an adjunct to usual care vs usual care

Remission · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care probably leads to higher remission (< 7 on HAMD or < 10 on BDI) medium term (7 to 12 months)* compared with usual care alone (moderate certainty).

2 findings from 1 review

Psychotherapy as an adjunct to usual care vs usual care

> 50% reduction in depressive symptoms · treatment‐resistant depression in adults

Psychotherapy as an adjunct to usual care may leads to higher response (50% reduction in depressive symptoms from baseline) short… compared with usual care alone (low certainty).

1 finding from 1 review

Mindfulness‐based cognitive therapy (MBCT) vs treatment

Incidence of SAD (IDS‐SR > 20) · adults with a history of SAD but without depressive symptoms when treatment started

It is very uncertain whether mindfulness‐based cognitive therapy (MBCT) changes incidence of SAD (IDS‐SR > 20) compared with treatment (very low certainty).

1 finding from 1 review

Mindfulness‐based cognitive therapy (MBCT) vs treatment

Overall discontinuation ( · adults with a history of SAD but without depressive symptoms when treatment started

It is very uncertain whether mindfulness‐based cognitive therapy (MBCT) changes overall discontinuation rate compared with treatment (very low certainty).

1 finding from 1 review

Dynamic‐Deconstructive Psychotherapy (DDP) vs treatment

Parasuicidalityno. of participants with parasuicide (last 3 months) · patients with borderline personality disorder

Dynamic‐Deconstructive Psychotherapy (DDP) showed no clear difference in parasuicidalityno. of participants with parasuicide (last 3 months) compared with treatment (low certainty).

1 finding from 1 review

Cognitive behaviour therapy + treatment‐as‐usual vs usual care

Physical aggression · adults with antisocial personality disorder

Cognitive behaviour therapy + treatment‐as‐usual showed no clear difference in aggression (any act of physical aggression) Assessed by: number… compared with treatment‐as‐usual alone (low certainty).

1 finding from 1 review