Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

369 questions · 377 findings · 28 reviews · Schizophrenia

No studies found 101 · 26.8%GRADE not reported 54 · 14.3%Very low 133 · 35.3%Low 63 · 16.7%Moderate 26 · 6.9%High 0 · 0%

Sildenafil vs placebo

Leaving the study early · patients with sexual dysfunction due to antipsychotic drug therapy

It is very uncertain whether ADJUNCTIVE TREATMENT ‐ SPECIFIC: SILDENAFIL changes leaving the study early compared with PLACEBO (very low certainty).

1 finding from 1 review

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)

Service use: Number of participants needing admission · Adolescents with psychosis

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) showed no clear difference in service use: Number of participants needing admission compared with NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term) (low certainty).

1 finding from 1 review