Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

761 questions · 801 findings · 50 reviews · Common Mental Disorders

No studies found 125 · 15.6%GRADE not reported 34 · 4.2%Very low 226 · 28.2%Low 232 · 29%Moderate 176 · 22%High 8 · 1%

Stand‐alone couple or family therapy vs other structured or non‐specific intervention

Dropout · post‐traumatic stress disorder (PTSD)

Stand‐alone couple or family therapy showed no clear difference in treatment dropout (treatment acceptability) compared with other structured or non‐specific intervention (low certainty).

1 finding from 1 review

S‐adenosyl methionine as monotherapy vs tricyclic antidepressants (TCAs)

Acceptability. Participants experiencing troublesome adverse effects of any nature · depression in adults

S‐adenosyl methionine as monotherapy may leads to lower acceptability. Participants experiencing troublesome adverse effects… compared with tricyclic antidepressant agent (low certainty).

1 finding from 1 review