Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

373 questions · 383 findings · 25 reviews · Hepato-Biliary

No studies found 62 · 16.2%GRADE not reported 3 · 0.8%Very low 259 · 67.6%Low 51 · 13.3%Moderate 7 · 1.8%High 1 · 0.3%

Intervention not reported

Aldosterone antagonists plus loop diuretics (3 RCTs; 125 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (3 RCTs; 125 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Transjugular intrahepatic portosystemic shunt (6 RCTs; 392 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (6 RCTs; 392… (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (4 RCTs; 211 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (4 RCTs; 211 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus paracentesis plus fluid replacement (1 RCT; 36 participants) · people with liver cirrhosis and ascites

The intervention may leads to higher aldosterone antagonists plus paracentesis plus fluid replacement (1… (low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics (4 RCTs; 242 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics (4 RCTs; 242 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (3 RCTs; 114 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (3 RCTs; 114 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Paracentesis plus systemic vasoconstrictors (5 RCTs; 165 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes paracentesis plus systemic vasoconstrictors (5 RCTs; 165 participants) (very low certainty).

1 finding from 1 review

Intervention not reported

Aldosterone antagonists plus loop diuretics plus paracentesis plus fluid replacement (No direct RCT) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes aldosterone antagonists plus loop diuretics plus paracentesis plus… (very low certainty).

1 finding from 1 review

Intervention not reported

Transjugular intrahepatic portosystemic shunt (7 RCTs; 452 participants) · people with liver cirrhosis and ascites

It is very uncertain whether the intervention changes transjugular intrahepatic portosystemic shunt (7 RCTs; 452… (very low certainty).

1 finding from 1 review